Hirano Yoshiyuki, Nishikido Fumihiko, Kokuryo Daisuke, Yamaya Taiga
Molecular Imaging Center, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
Gunma University, 3-39-22 Showa-Machi, Maebashi, Gunma, 371-8511, Japan.
Radiol Phys Technol. 2016 Jul;9(2):245-53. doi: 10.1007/s12194-016-0356-3. Epub 2016 May 17.
Multi-pixel photon counters (MPPCs) have been used instead of photomultiplier tubes for positron emission tomography combined with magnetic resonance (PET-MR). However, the effects of the magnetic field (MF) on the intrinsic properties-gain, cross-talk, after-pulsing, and dark-count-have not been sufficiently investigated. Therefore, we measured these properties for two types of MPPCs-S10931-50P and S12572-50P-in a static 7-T MF. These properties were measured with a pulse-shape analysis using pulse data acquired by a digital oscilloscope in the presence of the MF (w/MF) and the absence of the MF (w/o MF) by changing the supplied over-voltages (from 0.95 to 2.1 V for S10931 and from 2.1 to 3.3 V for S12572). No significant differences between the w/MF and w/o MF cases were observed for either MPPC, suggesting that the gain, cross-talk, after-pulsing, and dark-count are insensitive to a 7-T MF. The present work shows that constant MPPC performance is expected under a strong MF and demonstrates positive results for PET-MR.
在正电子发射断层扫描与磁共振成像相结合(PET-MR)中,多像素光子计数器(MPPC)已被用于替代光电倍增管。然而,磁场(MF)对其固有特性——增益、串扰、后脉冲和暗计数的影响尚未得到充分研究。因此,我们在7-T静态磁场中测量了两种类型的MPPC(S10931-50P和S12572-50P)的这些特性。通过使用数字示波器采集的脉冲数据,在有磁场(w/MF)和无磁场(w/o MF)的情况下,通过改变施加的过电压(S10931为0.95至2.1 V,S12572为2.1至3.3 V),采用脉冲形状分析来测量这些特性。两种MPPC在有磁场和无磁场情况下均未观察到显著差异,这表明增益、串扰、后脉冲和暗计数对7-T磁场不敏感。目前的工作表明,在强磁场下MPPC性能有望保持恒定,并为PET-MR展示了积极的结果。