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[喀麦隆雅温得中心医院献血者的艾滋病毒及风险因素]

[HIV and risk factors for the blood donors at the central hospital of Yaounde, Cameroon].

作者信息

Mole S, Onana E, Biholong D

机构信息

Banque du sang de l'hôpital central de Yaoundé, Yaoundé, Cameroun.

出版信息

Bull Soc Pathol Exot. 2011 Aug;104(3):226-31. doi: 10.1007/s13149-011-0163-3. Epub 2011 Jun 21.

DOI:10.1007/s13149-011-0163-3
PMID:21695495
Abstract

The HIV/AIDS infection is in a permanent progress in Cameroon. Through this descriptive and analytical cross-sectional study, we aimed to compare the occurrence of the HIV by taking into account the risks factors that are significantly associated with HIV. The investigation was carried out from 1 January till 31 December 2009 in the Blood Bank of the Central Hospital of Yaounde in Cameroon. A structured questionnaire was proposed to collect socio-demographic and risk behavioral information. Venous blood was collected for HIV antibody testing. Generalized estimating equation with logistic regression was used to analyze the risk factors for HIV infection. In all, 5 058 persons were included in this study. Serological examination revealed a total prevalence of 5.4% of HIV infection in the population studied. The family/replacement donors constituted the majority (69.5%) and showed a higher risk of seropositivity of HIV than the benevolent donors in raw analysis; but after adjustment, the family donors had the same risk of seropositivity of HIV than voluntary blood donors (aOR = 1.00). Variables such as homosexual intercourse (aOR = 1.61), to have already made a screening test of HIV (aOR = 1.83), mobility (aOR = 2.24), treatment and records of STI (aOR = 3.81), use of the condom (aOR = 6.63), more than one sexual partner (aOR = 8.40) remained significantly linked to the result of the HIV serology and constituted risk factors that will be emphasized during the selection of the donors.

摘要

在喀麦隆,艾滋病毒/艾滋病感染情况呈持续发展态势。通过这项描述性和分析性横断面研究,我们旨在考虑与艾滋病毒显著相关的风险因素,比较艾滋病毒的感染情况。调查于2009年1月1日至12月31日在喀麦隆雅温得中心医院血库进行。采用结构化问卷收集社会人口统计学和风险行为信息。采集静脉血进行艾滋病毒抗体检测。使用广义估计方程和逻辑回归分析艾滋病毒感染的风险因素。本研究共纳入5058人。血清学检查显示,在所研究人群中艾滋病毒感染的总患病率为5.4%。家庭/替代献血者占大多数(69.5%),在初步分析中,其艾滋病毒血清阳性风险高于慈善献血者;但经过调整后,家庭献血者与自愿献血者的艾滋病毒血清阳性风险相同(调整后比值比=1.00)。诸如同性性行为(调整后比值比=1.61)、曾进行过艾滋病毒筛查检测(调整后比值比=1.83)、流动性(调整后比值比=2.24)、性传播感染的治疗和记录(调整后比值比=3.81)、使用避孕套(调整后比值比=6.63)、有不止一个性伴侣(调整后比值比=8.40)等变量仍与艾滋病毒血清学结果显著相关,构成了在献血者选择过程中需要重点关注的风险因素。

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