Reproductive Life Stages, Women's College Hospital, Toronto, Canada.
Arch Womens Ment Health. 2011 Aug;14(4):325-33. doi: 10.1007/s00737-011-0223-5. Epub 2011 Jun 22.
Perinatal depression currently receives considerable attention, but not all perinatal women presenting for psychiatric care are depressed. The Edinburgh Postnatal Depression Scale (EPDS) is now routinely administered, but high scores are interpreted as evidence for depressive illness only. This study examined psychiatric diagnoses and mean EPDS scores among perinatal women at a tertiary center. Women accessing care between March 2006 and June 2008 completed a clinical diagnostic interview and the EPDS. Mean EPDS scores were calculated for each psychiatric diagnosis; sensitivity and specificity were calculated for major depressive episode (MDE) and generalized anxiety disorder (GAD). The majority of the sample (N = 91), 49.5%, had GAD comorbid with MDE or another anxiety disorder, followed by MDE (38.5%) comorbid with an anxiety disorder. One third (29.7%) met criteria for MDE and GAD. Only 3.3% had MDE alone and 5.5% had GAD alone. Half the sample (50.5%) had more than one psychiatric disorder. Mean EPDS scores exceeded 11 for the majority of diagnostic groups. Sensitivity of the EPDS for MDE was 0.78 and 0.70 for GAD. Most women had an anxiety disorder and met criteria for more than one psychiatric disorder. Mean EPDS scores were consistently high. Sensitivity of the EPDS for MDE and GAD was comparable.
目前,围产期抑郁症受到了相当多的关注,但并非所有接受精神科治疗的围产期妇女都患有抑郁症。现在常规使用爱丁堡产后抑郁量表(EPDS),但高分仅被解释为抑郁疾病的证据。本研究检查了三级中心围产期妇女的精神诊断和平均 EPDS 评分。2006 年 3 月至 2008 年 6 月期间就诊的女性完成了临床诊断访谈和 EPDS。为每个精神诊断计算了平均 EPDS 评分;计算了主要抑郁发作(MDE)和广泛性焦虑障碍(GAD)的敏感性和特异性。大多数样本(N=91),49.5%,患有 GAD 合并 MDE 或另一种焦虑症,其次是 MDE(38.5%)合并焦虑症。三分之一(29.7%)符合 MDE 和 GAD 的标准。仅有 3.3%的人仅有 MDE,5.5%的人仅有 GAD。一半的样本(50.5%)有多种精神障碍。大多数诊断组的平均 EPDS 评分超过 11。EPDS 对 MDE 的敏感性为 0.78,对 GAD 的敏感性为 0.70。大多数女性患有焦虑症,并符合多种精神障碍的标准。平均 EPDS 评分一直很高。EPDS 对 MDE 和 GAD 的敏感性相当。