Baruteau Alban-Elouen, Martins Raphaël Pedro, Boulmier Dominique, Basquin Adeline, Briard David, Gandemer Virginie, Schleich Jean-Marc
Département de Cardiologie et Maladies Vasculaires, Centre Cardio-pneumologique, Hôpital Pontchaillou,Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, Rennes cedex 09, France. :
Congenit Heart Dis. 2012 Jan-Feb;7(1):76-9. doi: 10.1111/j.1747-0803.2011.00537.x. Epub 2011 Jun 22.
A 9-year-old black African boy was hospitalized for heart failure revealing a severe left ventricular dysfunction associated with dilated cardiomyopathy, two submitral aneurysms, occlusion of the circumflex artery and a giant coronary artery aneurysm on the proximal left anterior descending artery. The boy was coinfected with human immunodeficiency virus and Mycobacterium tuberculosis. Though rare, association of Takayasu arteritis and submitral aneurysm leads to rethinking the pathogenesis of submitral aneurysm and suggests that some of them may be acquired. In our case, a common inflammatory process, possibly triggered by tuberculosis or HIV, may underlie Takayasu and submitral aneurysms.
一名9岁的非洲黑人男孩因心力衰竭住院,检查发现严重的左心室功能障碍,伴有扩张型心肌病、二尖瓣下两个动脉瘤、回旋支动脉闭塞以及左前降支近端巨大冠状动脉瘤。该男孩同时感染了人类免疫缺陷病毒和结核分枝杆菌。虽然罕见,但高安动脉炎与二尖瓣下动脉瘤的关联促使人们重新思考二尖瓣下动脉瘤的发病机制,并提示其中一些可能是后天获得性的。在我们的病例中,一个可能由结核或艾滋病毒引发的共同炎症过程,可能是高安动脉炎和二尖瓣下动脉瘤的潜在病因。