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老年髋部骨折患者中帕金森综合征的患病率。

Prevalence of Parkinsonism in older patients with hip fracture.

作者信息

Yiannopoulou Konstantina G, Papageorgiou Sokratis G, Anastasiou Ioannis P, Ganetsos Theodore K, Karydakis Kleanthis D

机构信息

Department of Neurology, Laiko General Hospital of Athens, Athens - Greece.

出版信息

Hip Int. 2011 May-Jun;21(3):351-5. doi: 10.5301/HIP.2011.8402. Epub 2011 Jun 8.

DOI:10.5301/HIP.2011.8402
PMID:21698587
Abstract

Parkinsonism in hip fracture (HF) patients is a potential source for complications during surgery, postoperative period and rehabilitation and a risk factor of second HF. We investigated whether parkinsonism was more prevalent in older subjects with HF than in other older patient groups undergoing surgery. We prospectively assessed patients who had suffered HF and controls. We assigned all patients aged 68 and older admitted in our hospital for HF surgery during last year and compared them with age- and gender matched patients attending other surgical departments. 80 HF patients and 80 controls were assessed for parkinsonism. Parkinsonism was common in both groups, presumably reflecting the mean ages of approximately 80 years, plus hospitalization-status. However, parkinsonism was much higher in the hip fracture group (76.25%) compared to the control hospitalised subjects (37.5%; p<0.001). The majority of HF patients with parkinsonism were undiagnosed for their parkinsonism symptoms prior to HF and the same was observed in the control group (91.8% and 86.7% respectively, p= 0.471). Among those with parkinsonism, pre-hospitalization drug therapy may have been contributory in 24.5% of HF patients and 30% of controls (p=0.589). Parkinsonism is very common in older patients admitted for surgery to a general hospital and extremely common in those with HF. It seems that parkinsonism, is heavily under recognised in the elderly. Our data seem to confirm that parkinsonism is a major risk factor of HF in the elderly.

摘要

髋部骨折(HF)患者的帕金森症是手术、术后及康复期间并发症的潜在来源,也是再次发生髋部骨折的危险因素。我们调查了患有髋部骨折的老年患者中帕金森症是否比其他接受手术的老年患者群体更普遍。我们对髋部骨折患者和对照组进行了前瞻性评估。我们纳入了去年在我院因髋部骨折手术入院的所有68岁及以上患者,并将他们与其他外科科室年龄和性别匹配的患者进行比较。对80名髋部骨折患者和80名对照者进行了帕金森症评估。帕金森症在两组中都很常见,这可能反映了平均年龄约80岁以及住院状态。然而,髋部骨折组的帕金森症发生率(76.25%)远高于对照组住院患者(37.5%;p<0.001)。大多数患有帕金森症的髋部骨折患者在发生髋部骨折之前其帕金森症症状未被诊断出来,对照组情况相同(分别为91.8%和86.7%,p = 0.471)。在患有帕金森症的患者中,24.5%的髋部骨折患者和30%的对照者在住院前可能接受过药物治疗(p = 0.589)。帕金森症在综合医院接受手术的老年患者中非常常见,在髋部骨折患者中极为常见。似乎帕金森症在老年人中严重未被认识到。我们的数据似乎证实帕金森症是老年人髋部骨折的主要危险因素。

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