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电针可减轻大鼠缺血后脑水肿。

Electro-acupuncture can alleviate the cerebral oedema of rat after ischemia.

作者信息

Zhang Feng, Wu Yi, Jia Jie

机构信息

Department of Rehabilitation, Huashan Hospital, Fudan University, WuLuMuQi Middle Road 12, Shanghai, PR China.

出版信息

Brain Inj. 2011;25(9):895-900. doi: 10.3109/02699052.2011.581639. Epub 2011 Jun 23.

DOI:10.3109/02699052.2011.581639
PMID:21699400
Abstract

PRIMARY OBJECTIVE

This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia.

RESEARCH DESIGN

EA has been widely used for cerebrovascular disease in East Asian countries. However, whether EA might reduce cerebral oedema after stroke remains unclear. In the current study, diffusion-weighted MRI, which is a reliable method for detecting cerebral oedema, was used to determine whether EA could ameliorate cerebral oedema.

METHODS AND PROCEDURES

Twelve rats with induced strokes were divided into two groups: one group with EA treatment (EA group) and one group without EA treatment (non-EA group). Both groups of rats underwent MRI scanning at the same time point following ischemia.

MAIN OUTCOMES AND RESULTS

Diffusion-weighted imaging showed that the relative apparent diffusion coefficient increased significantly in the cortical and sub-cortical areas of the EA group relative to the non-EA group, indicating that EA can alleviate cerebral oedema after ischemic stroke.

CONCLUSIONS

Electro-acupuncture can alleviate cerebral oedema in rats following ischemia.

摘要

主要目的

本研究旨在确定电针(EA)是否能减轻脑缺血后的脑水肿。

研究设计

电针在东亚国家已被广泛用于治疗脑血管疾病。然而,电针是否能减轻中风后的脑水肿仍不清楚。在本研究中,弥散加权磁共振成像(一种检测脑水肿的可靠方法)被用于确定电针是否能改善脑水肿。

方法与步骤

12只诱导中风的大鼠被分为两组:一组接受电针治疗(电针组),一组不接受电针治疗(非电针组)。两组大鼠在缺血后的同一时间点接受磁共振成像扫描。

主要结果

弥散加权成像显示,相对于非电针组,电针组皮质和皮质下区域的相对表观扩散系数显著增加,表明电针可减轻缺血性中风后的脑水肿。

结论

电针可减轻大鼠缺血后的脑水肿。

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