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脂肪酸ω-6和ω-3在发育过程中的依赖性及不同作用。

Developmentally dependent and different roles of fatty acids OMEGA-6 and OMEGA-3.

作者信息

Mourek J, Mourek J

机构信息

Faculty of Health and Social Studies, University of South Bohemia, České Budějovice, Czech Republic.

出版信息

Prague Med Rep. 2011;112(2):81-92.

PMID:21699757
Abstract

The developmentally-dependent differences in the biological significances and effects of PUFA-OMEGA-6 (namely of arachidonic acid) and PUFA-OMEGA-3 (namely of docosahexaenoic acid) are discussed. The clinical results as well as developmental experiences are indicating a hypothesis of the evolution that created mutual relationship between those two substances (with immunological basis and following recuperation). The anti-inflammatory actions of PUFA-OMEGA-3 are the most visible (and significant) contrasts as compared with the large affects of namely arachidonic acid and its metabolites.

摘要

本文讨论了多不饱和脂肪酸-ω-6(即花生四烯酸)和多不饱和脂肪酸-ω-3(即二十二碳六烯酸)在生物学意义和作用上的发育依赖性差异。临床结果以及发育方面的经验表明了一种进化假说,该假说认为这两种物质之间存在相互关系(具有免疫学基础并随之恢复)。与花生四烯酸及其代谢产物的大量影响相比,多不饱和脂肪酸-ω-3的抗炎作用是最明显(且显著)的对比。

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