Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, 201 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, 473 W. 12th Avenue, Columbus, OH 43210, USA.
Respir Med. 2011 Oct;105(10):1434-40. doi: 10.1016/j.rmed.2011.05.015. Epub 2011 Jun 22.
Asthma is one of the most common medical conditions complicating pregnancy. Despite the presence of published guidelines outlining the care of the pregnant patient with asthma, disparities in the treatment of acute asthma exacerbations in the emergency department related to pregnancy status are known to exist. We sought to determine if pregnancy status affected the treatment of women presenting to a tertiary emergency department for care of acute asthma exacerbations.
We retrospectively compared the emergency department treatment of acute asthma exacerbations in 123 pregnant women to 123 non-pregnant controls. Asthma exacerbations were classified by severity according to pre-determined criteria.
In the emergency department (ED), pregnant women were significantly less likely to be treated with systemic corticosteroids than non-pregnant controls (50.8% versus 72.4%, p = 0.001). Similarly, 41% of pregnant women received prescriptions for prednisone at the time of discharge from the ED compared to 69.2% of non-pregnant women (p < 0.001).
In this population of asthmatics presenting to a tertiary emergency department with acute asthma exacerbations, pregnant women were less likely to receive appropriate therapy with systemic corticosteroids.
哮喘是妊娠常见合并症之一。尽管已有发表的指南概述了哮喘孕妇的护理方法，但已知在与妊娠状态相关的急诊科急性哮喘发作的治疗中存在差异。我们试图确定妊娠状态是否会影响到因急性哮喘加重而到三级急诊科就诊的女性的治疗。
我们回顾性比较了 123 例妊娠妇女和 123 例非妊娠对照者在急诊科治疗急性哮喘加重的情况。根据预先确定的标准，将哮喘加重分为严重程度。
在急诊科，与非妊娠对照组相比，孕妇接受全身皮质类固醇治疗的可能性明显较低（50.8%对 72.4%，p=0.001）。同样，与非妊娠妇女（69.2%）相比，在急诊科出院时，41%的孕妇开具了泼尼松的处方（p<0.001）。
在因急性哮喘加重而到三级急诊科就诊的哮喘患者中，孕妇接受全身皮质类固醇治疗的可能性较低。
