Famanta Aminata, Diakite Mahamadou, Diawara Sory Ibrahim, Diakité Seidina A, Doumbia Saibou, Traoré Karim, Konaté Drissa S, Doumbia Mory, Keita Abdoul Salam, Thiéro Daouda, Traoré Sékou Fantamady, Doumbia Seydou, Tounkara Anatole
Universite de Bamako, Bamako, Mali.
Sante. 2011 Jan-Mar;21(1):3-7. doi: 10.1684/san.2011.0234.
In 2006, the Malian government established a program for free insecticide-treated net (ITNs) distribution during antenatal care visit (ANC) and intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) for pregnant women. In March to November of 2009, we conducted a cross-sectional study in peri-urban areas of Bamako, Mali to determine the malaria prevalence among pregnant women and their newborn children in the context of this policy. We included 379 pregnant women aged 15 to 45 years. At delivery, malaria was diagnosed using peripheral thick smears in mothers and newborns, as well as umbilical cord blood and placental blood. The prevalence of Plasmodium falciparum malaria was 2.4, 1.6 and 0.5% respectively in mother, placenta and cord samples; we observed a low birth weight rate of 12.1%. Approximately 77% of our parturient were housewives. The illiteracy rate among this group was 72.3%. Of the 379 women, 73% had at least three prenatal visits, 83% had received at least one free ITNs and 72% had received IPTp-SP during antenatal visit. Among them, 81% claimed to have complied with IPTp-SP. No congenital malaria was found. The prevalence of malaria in both mother and newborn has show a significant decrease in Bamako, compared with previous studies before the implementation of IPTp-SP policy in Mali. A high rate of coverage and use of IPTp-SP and ITNs correlate with lower malaria prevalence in pregnant women.
2006年，马里政府制定了一项计划，在产前检查（ANC）期间免费发放经杀虫剂处理的蚊帐（ITNs），并对孕妇进行磺胺多辛-乙胺嘧啶间歇性预防治疗（IPTp-SP）。2009年3月至11月，我们在马里巴马科的城郊地区开展了一项横断面研究，以确定在这一政策背景下孕妇及其新生儿中的疟疾流行情况。我们纳入了379名年龄在15至45岁之间的孕妇。分娩时，通过对母亲和新生儿的外周厚涂片以及脐带血和胎盘血进行检测来诊断疟疾。母亲、胎盘和脐带样本中恶性疟原虫疟疾的患病率分别为2.4%、1.6%和0.5%；我们观察到低出生体重率为12.1%。我们的产妇中约77%是家庭主妇。该群体中的文盲率为72.3%。在这379名妇女中，73%至少进行了三次产前检查，83%至少领取了一顶免费ITNs，72%在产前检查期间接受了IPTp-SP。其中，81%声称遵守了IPTp-SP。未发现先天性疟疾。与马里实施IPTp-SP政策之前的先前研究相比，巴马科母亲和新生儿中的疟疾患病率均显著下降。IPTp-SP和ITNs的高覆盖率和使用率与孕妇中较低的疟疾患病率相关。
