University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
AJNR Am J Neuroradiol. 2011 Aug;32(7):1216-20. doi: 10.3174/ajnr.A2515. Epub 2011 Jun 23.
There is no satisfactory parameter that can predict the need for assistant devices for endovascular aneurysm coiling. Our aim was to evaluate the utility of MOA as a predictor of the need for stent-assisted coiling in ICA sidewall aneurysms.
From a retrospective review of an internal data base, 55 consecutive ICA sidewall aneurysms were identified. Thirty-two of the aneurysms were treated by using endovascular techniques. Because 23 of the 55 aneurysms were either untreated or clipped, 3 experienced interventionalists reviewed the 3D images of these aneurysms and then made a decision as to whether stent-assisted coiling would have been required. Thirty-one of the 55 aneurysms would have required stent-assisted coiling, while 24 would not. Neck width, DNR, AR, and MOA were obtained from each aneurysm by using prototype software. These parameters were then correlated with the requirement of stent-assisted coiling.
MOA and neck width of aneurysms requiring stent-assisted coiling were significantly larger than those not requiring stent-assisted coiling (P < .001 and <0.001, respectively). Although the DNR and AR of aneurysms requiring stent-assisted coiling were smaller than those not requiring it, the difference was not significant (P = .22 and 0.12, respectively). ROC analysis revealed that MOA was the parameter that best correlated with the need for stent-assisted coiling. Inclusion of MOA with the rest of the parameters significantly increased the predictive performance regarding the need for stent-assisted coiling (P = .005).
In this small study, MOA was a useful parameter to predict the need for stent-assisted coiling in ICA sidewall aneurysms. Further prospective study of this parameter for aneurysms at multiple locations is required to determine its ultimate value.
目前尚无能够预测血管内动脉瘤弹簧圈栓塞辅助器械需求的理想参数。本研究旨在评估 MOA 作为颈内动脉(ICA)侧壁动脉瘤支架辅助弹簧圈栓塞适应证的预测因子的效用。
对内部数据库的回顾性分析共确定了 55 例连续的 ICA 侧壁动脉瘤,其中 32 例接受了血管内治疗。因为 55 个动脉瘤中有 23 个未治疗或夹闭,所以 3 名介入专家对这 23 个动脉瘤的 3D 图像进行了评估,以确定是否需要支架辅助弹簧圈栓塞。55 个动脉瘤中有 31 个需要支架辅助弹簧圈栓塞,24 个不需要。通过原型软件获得每个动脉瘤的颈宽、瘤颈非狭窄率(DNR)、瘤颈狭窄率(AR)和 MOA。然后将这些参数与支架辅助弹簧圈栓塞的需求相关联。
需要支架辅助弹簧圈栓塞的动脉瘤的 MOA 和颈宽明显大于不需要支架辅助弹簧圈栓塞的动脉瘤(P<0.001 和 P<0.001)。虽然需要支架辅助弹簧圈栓塞的动脉瘤的 DNR 和 AR 小于不需要支架辅助弹簧圈栓塞的动脉瘤,但差异无统计学意义(P=0.22 和 0.12)。ROC 分析显示,MOA 是与支架辅助弹簧圈栓塞需求最相关的参数。将 MOA 与其他参数相结合,可显著提高支架辅助弹簧圈栓塞需求的预测性能(P=0.005)。
在这项小型研究中,MOA 是预测 ICA 侧壁动脉瘤支架辅助弹簧圈栓塞需求的有用参数。需要对多个部位的动脉瘤进行该参数的前瞻性研究,以确定其最终价值。