Keio University School of Medicine, Tokyo, Japan.
Neurorehabil Neural Repair. 2011 Oct;25(8):711-20. doi: 10.1177/1545968311407516. Epub 2011 Jun 23.
and objective. Unilateral spatial neglect (USN) can interfere with rehabilitation processes and lead to poor functional outcome. The purpose of this study was to determine whether prism adaptation (PA) therapy improves USN and functional outcomes in stroke patients in the subacute stage.
. A multicenter, double-masked, randomized, controlled trial was conducted to evaluate the effects of a 2-week PA therapy on USN assessed with the Behavioral Inattention Test (BIT), the Catherine Bergego Scale (CBS), and activities of daily living (ADL) as evaluated with the Functional Independence Measure (FIM). A total of 38 USN patients with right-brain damage were divided into prism (n = 20) and control (n = 18) groups. Patients were divided into mild and severe USN groups according to BIT behavioral test (mild ≥ 55 and severe<55). The prism group performed repetitive pointing with prism glasses that induce rightward optical shift twice daily, 5 days per week, for 2 weeks, whereas the control group performed similar pointing training with neutral glasses.
. The FIM improved significantly more in the prism group. In mild USN patients, there was significantly greater improvement of BIT and FIM in the prism group.
. PA therapy can significantly improve ADL in patients with subacute stroke.
单侧空间忽略（USN）会干扰康复过程，导致功能预后不良。本研究旨在确定棱镜适应（PA）疗法是否能改善亚急性期脑卒中患者的 USN 和功能预后。
进行了一项多中心、双盲、随机、对照试验，以评估为期 2 周的 PA 疗法对 USN 的影响，使用行为忽视测试（BIT）、凯瑟琳·贝戈量表（CBS）和日常生活活动（ADL）评估功能性独立测量（FIM）。共有 38 名右脑损伤的 USN 患者分为棱镜（n=20）和对照组（n=18）。根据 BIT 行为测试将患者分为轻度（≥55）和重度 USN 组（<55）。棱镜组每天两次使用棱镜眼镜进行重复指向训练，以产生向右的光学移位，每周 5 天，持续 2 周，而对照组则使用中性眼镜进行类似的指向训练。
FIM 明显改善，棱镜组改善更显著。在轻度 USN 患者中，棱镜组的 BIT 和 FIM 显著改善。
PA 疗法可显著改善亚急性期脑卒中患者的 ADL。
