Depto. de Biología Celular y Fisiología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México DF, México.
Reprod Sci. 2011 Dec;18(12):1246-52. doi: 10.1177/1933719111411728. Epub 2011 Jun 23.
Temporal and coordinated activation of pelvic- (pubococcygeous) and perineal- (bulbospongiosus and ischiocavernosus) striated muscles occurs during micturition in female rabbits. We have hypothesized that the coordinated activation of pelvic and perineal muscles is modified during the micturition of young multiparous rabbits. Young virgin and multiparous female chinchilla rabbits were used to simultaneously record cystometrograms and electromyograms of the pubococcygeous, ischocavernosus, and bulbospongiosus muscles. Bladder function was assessed using standard urodynamic variables. The temporal coordination of pelvic- and perineal-striated muscle activity was changed in multiparous rabbits. The cystometrogram recordings were different than those obtained from virgin rabbits, as seen in alterations of the threshold volume, the residual volume, the voiding duration, and the maximum pressure. In rabbits, we find that multiparity causes uncoordinated activity of pubococcygeous, ischiocavernosus, and bulbospongiosus muscles and modifies the urodynamics.
在雌性兔子的排尿过程中，骨盆-（耻骨尾骨肌）和会阴-（球海绵体肌和坐骨海绵体肌）横纹肌会出现时间和协调的激活。我们假设，在年轻多产兔子的排尿过程中，骨盆和会阴肌肉的协调激活会发生改变。年轻的处女和多产的雌性龙猫兔被用来同时记录耻骨尾骨肌、坐骨海绵体肌和球海绵体肌的肌电图和尿动力学图。膀胱功能使用标准尿动力学变量进行评估。多产兔子的骨盆和会阴横纹肌活动的时间协调性发生了变化。尿动力学图的记录与处女兔的不同，表现为阈值容积、残余容积、排空时间和最大压力的改变。在兔子中，我们发现多产会导致耻骨尾骨肌、坐骨海绵体肌和球海绵体肌的不协调活动，并改变尿动力学。
