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Angiotensin II B-type receptor mediates phosphoinositide hydrolysis in mesangial cells.

作者信息

Pfeilschifter J

机构信息

Research Department, Pharmaceuticals Division, Ciba-Geigy Ltd., Basel, Switzerland.

出版信息

Eur J Pharmacol. 1990 Aug 2;184(1):201-2. doi: 10.1016/0014-2999(90)90684-x.

DOI:10.1016/0014-2999(90)90684-x
PMID:2170150
Abstract
摘要

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Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C-epsilon in rat renal mesangial cells.细胞外ATP和UTP对磷脂酶D的激活作用由大鼠肾系膜细胞中的蛋白激酶C-ε介导。
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Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells.
细胞因子刺激大鼠系膜细胞分泌II型磷脂酶A2。其对培养的大鼠肾小球细胞花生四烯酸释放和前列腺素合成的作用。
J Clin Invest. 1993 Nov;92(5):2516-23. doi: 10.1172/JCI116860.
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Stimulation by extracellular ATP and UTP of the mitogen-activated protein kinase cascade and proliferation of rat renal mesangial cells.细胞外ATP和UTP对大鼠肾系膜细胞丝裂原活化蛋白激酶级联反应的刺激及细胞增殖作用。
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Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain.血管紧张素II受体亚型与大鼠脑神经元和星形胶质细胞中不同的信号转导机制相关联。
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