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[呼吸中枢神经元过度激活时的呼吸调节]

[Respiratory regulation during neuronal hyperactivation of the respiratory center].

作者信息

Kryzhanovskiĭ G N, Kanaĭkina E R, Kim A V, Lebedeva M A, Safonov V A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1990 May;76(5):595-603.

PMID:2170192
Abstract

The responses of breathing and of respiratory neurons to microinjections of penicillin into the respiratory center area were studied in anesthetized and spontaneously breathing rats. The injections caused different alterations of the respiration, of the activity of respiratory neurons and their spatial distribution, and initiated respiratory moments of apneustic and gasping types. the hyperactivation of the respiratory center neurons by penicillin seems to cause a reversible development of pathological types of respiration.

摘要

在麻醉和自主呼吸的大鼠中,研究了向呼吸中枢区域微量注射青霉素后呼吸及呼吸神经元的反应。注射导致呼吸、呼吸神经元活动及其空间分布出现不同改变,并引发长吸式和喘息式呼吸瞬间。青霉素对呼吸中枢神经元的过度激活似乎会导致病理性呼吸类型的可逆发展。

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