Naveed Tahir, Ayub Muhammad, Nazeer Mohsin, Mallick Nadeem Hayat, Mohydin Bilal S, Ali Zulfiqar
Department of Cardiology, Punjab Intitute of Cardiology, Lahore, Pakistan.
J Ayub Med Coll Abbottabad. 2010 Apr-Jun;22(2):13-9.
Coronary artery bypass graft surgery is a commonly performed revascularization procedure in ischemic heart disease patients. Conventional coronary angiography is an invasive method for evaluation of grafts in such patients. Non-invasive evaluation of grafts in post CABG patient has been made possible with the advent of 64-Slice Multi Detector Computed Tomography (MDCT) The Objective of the study was to non-invasively assess the graft patency with MDCT.
Sixty post CABG patients (52 male, 8 female) with atypical chest pain or stable angina were evaluated with MDCT for graft patency. The grafts were considered as patent if there was continuous lumen visualisation at origin, in the body and at its insertion with native recipient vessels. Grafts were defined as blocked when only stumps were seen. They were classified as stenotic if there was > or = 50% diameter narrowing.
The mean age of the patients was 60.1 +/- 9.7 years, mean duration since CABG was 8.01 +/- 6 years. Total number of grafts assessed was 175 including 124 (71%) venous grafts and 51 (28.9%) arterial grafts. A total of 82/124 (66.1%) venous grafts and 47/51 (92%) arterial grafts were patent. Forty-two (34%) venous grafts were blocked whereas 4 arterial grafts were not developed. Arterial grafts patency was 92% and venous grafts patency was 67.7% after a mean follow up of 8.01 +/- 6 years.
The study shows that 64 slice MDCT can be used for the evaluation of patency and occlusion of venous and arterial grafts in post CABG patients for follow up.
冠状动脉旁路移植术是缺血性心脏病患者常用的血管重建手术。传统冠状动脉造影是评估此类患者移植血管的侵入性方法。64层螺旋多排计算机断层扫描(MDCT)的出现使得对冠状动脉旁路移植术(CABG)后患者的移植血管进行无创评估成为可能。本研究的目的是利用MDCT对移植血管通畅情况进行无创评估。
对60例有非典型胸痛或稳定型心绞痛的冠状动脉旁路移植术(CABG)后患者进行MDCT检查以评估移植血管通畅情况。如果在起源处、血管主体及其与天然受体血管的连接处有连续的管腔显影,则认为移植血管通畅。如果仅见残端,则移植血管定义为闭塞。如果直径狭窄≥50%,则分类为狭窄。
患者的平均年龄为60.1±9.7岁,冠状动脉旁路移植术后的平均时间为8.01±6年。评估的移植血管总数为175条,包括124条(71%)静脉移植血管和51条(28.9%)动脉移植血管。共有82/124(66.1%)条静脉移植血管和47/51(92%)条动脉移植血管通畅。42条(34%)静脉移植血管闭塞,而4条动脉移植血管未发育。平均随访8.01±6年后,动脉移植血管通畅率为92%,静脉移植血管通畅率为67.7%。
本研究表明,64层MDCT可用于冠状动脉旁路移植术(CABG)后患者静脉和动脉移植血管通畅和闭塞情况的评估以便进行随访。