Ahmed Muhammad Ejaz, Ahmad Iftikhar, Akhtar Saleem
Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.
J Ayub Med Coll Abbottabad. 2010 Apr-Jun;22(2):138-42.
Breast screening is a method of detecting breast cancer at a very early stage. Most of the lesions detected by screening are not malignant. Objective of this study was to compare ultrasound guided fine needle aspiration cytology and core biopsy in the preoperative assessment of non-palpable breast lesions.
The study was conducted prospectively at Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Pakistan from March 2004 to February 2005. All the patients underwent fine needle aspiration cytology and core biopsy. Later on, all of them had excision biopsy/mastectomy. Prospectively 80 patients were studied; information was collected on a specifically designed form according to inclusion criteria. The patient age, sex, medical record number and side of lesion were recorded. Clinical history of duration of lump was also taken. Informed consent was obtained.
The age of patients were ranges from 20-71 years, with mean of 44.31 +/- 11.002 and the maximum number of patients 28 (35.3%) was between the ages 50-59 years. The sensitivity of FNAC was 92.85%, while the specificity of was 90% and the accuracy rate was 92.1%. The sensitivity of core biopsy was 94.64%, specificity 91.30% and accuracy rate was 94.87%.
Fine Needle Aspiration has been found to be an extremely useful method for the diagnosis of lumps of breast. The accuracy and the sensitivity of diagnosis on fine needle aspiration cytology were high.
乳腺筛查是一种在极早期检测乳腺癌的方法。筛查发现的大多数病变并非恶性。本研究的目的是比较超声引导下细针穿刺细胞学检查和粗针活检在不可触及乳腺病变术前评估中的应用。
本研究于2004年3月至2005年2月在巴基斯坦沙卡特汗姆纪念癌症医院和研究中心放射科前瞻性开展。所有患者均接受了细针穿刺细胞学检查和粗针活检。随后，他们全部接受了切除活检/乳房切除术。前瞻性研究了80例患者；根据纳入标准在专门设计的表格上收集信息。记录患者的年龄、性别、病历号和病变部位。还记录了肿块持续时间的临床病史。获得了知情同意。
患者年龄在20 - 71岁之间，平均年龄为44.31 +/- 11.002岁，50 - 59岁的患者人数最多，为28例（35.3%）。细针穿刺细胞学检查的敏感性为92.85%，特异性为90%，准确率为92.1%。粗针活检的敏感性为94.64%，特异性为91.30%，准确率为94.87%。
细针穿刺已被发现是诊断乳腺肿块的一种极其有用的方法。细针穿刺细胞学检查的诊断准确性和敏感性较高。
