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[个体因素对化工行业工人的遗传毒性影响分析]

[Analysis of genotoxic effects of individual factors on chemical industry workers].

作者信息

Lunga I N, Trubnikov V I

出版信息

Gig Tr Prof Zabol. 1990(7):30-3.

PMID:2170240
Abstract

The article provides data on the study of occupational and non-occupational factors relating to the prevalence of early spontaneous abortions in couples engaged in fertilizer production. A higher degree prevalence of early spontaneous abortions was detected in several groups affected by specific factors. As this degree of prevalence was found in the groups in which it was only the father that had been exposed to the specific hazardous factors, it was considered that the factors in question either hindered the mutagen tolerance or were capable of their own germ cell mutagen action. It was established that lowered mutagen tolerance related to early abortions was markedly higher in groups exposed to organic substances' compounds and industrial noise.

摘要

本文提供了有关从事化肥生产的夫妇早期自然流产患病率相关职业和非职业因素研究的数据。在受特定因素影响的几个组中,检测到早期自然流产的患病率较高。由于在仅父亲接触特定危险因素的组中发现了这种患病率,因此认为所讨论的因素要么阻碍了诱变耐受性,要么自身具有生殖细胞诱变作用。已确定,与早期流产相关的诱变耐受性降低在接触有机物质化合物和工业噪声的组中明显更高。

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