Binnie N R, Kawimbe B M, Papachrysostomou M, Smith A N
University Department of Surgery, Western General Hospital, Edinburgh.
Gut. 1990 Sep;31(9):1051-5. doi: 10.1136/gut.31.9.1051.
An electrical stimulator has been devised to treat neurogenic faecal incontinence caused by pudendal nerve neuropathy and works on the basis of repeated stimulation of the pudendo-anal reflex arc. Although conduction in the pudendo-anal reflex arc may be prolonged, and is so in neurogenic faecal incontinence, it must be shown to be present before the method can be used. This stimulation results in an immediate rise in the pressure in the anal canal and a significant increase in the electromyographic activity of the external anal sphincter. Maintenance of the stimulus over a two month period raised the mean resting pressure significantly in the anal canal and increased the reflex and voluntary responses of the external anal sphincter to coughing and squeezing actions respectively. The length of the sphincter was not affected. There was widening of the mean motor unit potential duration, though this was not significant. The resting electromyogram was enhanced after the course of treatment, indicating greater spontaneous activity in the external sphincter. The changes led to seven of the eight patients studied becoming continent at the end of the treatment.
一种电刺激器已被设计用于治疗由阴部神经病变引起的神经源性大便失禁,其工作原理是反复刺激阴部 - 肛门反射弧。虽然阴部 - 肛门反射弧中的传导可能会延长,在神经源性大便失禁中也是如此,但在使用该方法之前必须证明其存在。这种刺激会导致肛管压力立即升高,肛门外括约肌的肌电图活动显著增加。在两个月的时间内持续进行刺激,可使肛管的平均静息压力显著升高,并分别增加肛门外括约肌对咳嗽和挤压动作的反射性和自主性反应。括约肌的长度未受影响。平均运动单位电位持续时间有所增宽,不过并不显著。治疗过程结束后,静息肌电图增强,表明肛门外括约肌的自发活动增强。这些变化使得所研究的八名患者中有七名在治疗结束时实现了大便自控。