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门诊患者低剂量脊髓麻醉下经尿道前列腺切除术(TURP):一项5年回顾

Transurethral resection of the prostate (TURP) with low dose spinal anesthesia in outpatients: a 5 year review.

作者信息

Sirivanasandha Busara, Lennox Pamela H, Vaghadia Himat

机构信息

Department of Anesthesia, Vancouver General Hospital, University of British Columbia, Canada.

出版信息

Can J Urol. 2011 Jun;18(3):5705-9.

Abstract

INTRODUCTION

Spinal anesthesia for ambulatory transurethral resection of the prostate (TURP) is a well established technique. The following study examines data over a 5 year period at a major Canadian tertiary academic center. The purpose of the study is to review our experience and complications associated with spinal anesthesia using combined low dose local anesthetic + narcotic for ambulatory TURP procedures.

METHODS

Medical records were reviewed retrospectively on all ambulatory TURP patients over a 5 year period between January 2000 and September 2005 in our Surgical Day Care Center. All spinal anesthetics were reviewed and based on dosage, classified into low dose bupivacaine (< 10 mg; Group LD-B), conventional dose lidocaine (> 35 mg; Group CD-L) or low dose lidocaine (≤ 35 mg; Group LD-L). Primary end points of interest were duration of spinal block and duration of postanesthesia care unit (PACU) stay.

RESULTS

A total of 1064 TURPs were performed during the study period. Within this cohort of 334 spinal anesthetics administered, 27 were excluded for lack of data leaving 307 cases for analysis. Patient demographics were normally distributed. Mean doses of spinal local anesthetics administered were: Group LD-B 7.3 ± 2 mg, Group CD-L 52.2 ± 13 mg and Group LD-L 29 ± 5.2 mg. Intrathecal fentanyl was often added to the local anesthetic as an adjunct. Block regression times (Group LD-B 273 ± 98 mins, Group CD-L 174 ± 47 mins and Group LD-L 159 ± 45 mins) and discharge times (Group LD-B 309 ± 94 mins, Group CD-L 230 ± 71 mins and Group LD-L 227 ± 75 mins) were significantly lesser in both lidocaine groups compared to Group LD-B (p <0.05). The frequency of prolonged spinal blocks (> 3 hr) in Groups LD-L, CD-L and LD-B was 23%, 43% and 83% respectively (p < 0.05).

CONCLUSION

Low dose spinal anesthesia with bupivacaine and lidocaine were well tolerated for short duration TURP. Low dose bupivacaine and conventional dose lidocaine were associated with significantly longer block duration, longer PACU stay and higher frequency of prolonged blocks compared with low dose lidocaine for spinal anesthesia.

摘要

引言

门诊经尿道前列腺切除术(TURP)的脊髓麻醉是一种成熟的技术。以下研究考察了加拿大一家大型三级学术中心5年期间的数据。本研究的目的是回顾我们在门诊TURP手术中使用低剂量局部麻醉药加麻醉性镇痛药联合脊髓麻醉的经验及并发症。

方法

回顾性分析了2000年1月至2005年9月期间在我们外科日间护理中心接受门诊TURP手术的所有患者的病历。对所有脊髓麻醉进行了回顾,并根据剂量分为低剂量布比卡因组(<10mg;LD-B组)、传统剂量利多卡因组(>35mg;CD-L组)或低剂量利多卡因组(≤35mg;LD-L组)。主要关注的终点是脊髓阻滞持续时间和麻醉后监护病房(PACU)停留时间。

结果

研究期间共进行了1064例TURP手术。在这334例实施脊髓麻醉的患者队列中,27例因数据缺失被排除,剩余307例用于分析。患者人口统计学数据呈正态分布。脊髓局部麻醉药的平均给药剂量为:LD-B组7.3±2mg,CD-L组52.2±13mg,LD-L组29±5.2mg。鞘内常添加芬太尼作为辅助用药。与LD-B组相比,两个利多卡因组的阻滞消退时间(LD-B组273±98分钟,CD-L组174±47分钟,LD-L组159±45分钟)和出院时间(LD-B组309±94分钟,CD-L组230±71分钟,LD-L组227±75分钟)明显更短(p<0.05)。LD-L组、CD-L组和LD-B组中脊髓阻滞延长(>3小时)的发生率分别为23%、43%和83%(p<0.05)。

结论

布比卡因和利多卡因低剂量脊髓麻醉对短时间TURP耐受性良好。与低剂量利多卡因脊髓麻醉相比,低剂量布比卡因和传统剂量利多卡因与明显更长的阻滞持续时间、更长的PACU停留时间以及更高的阻滞延长发生率相关。

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