Takaoka Liliana Aparecida Mendonça Vespoli, Goulart Ana Lucia, Kopelman Benjamin Israel, Weiler Rosa Maria Eid
Department of Pediatrics, Neonatal Division of Medicine, Federal University of São Paulo, São Paulo, Brazil.
Pediatr Dent. 2011 Mar-Apr;33(2):171-6.
This study's purpose was to compare the frequency of enamel defects (ED) in the complete primary dentition (CDD) of term children (TC) and preterm children (PTC) and to analyze neonatal factors associated with ED in PTC.
The study group was formed by 45 PTC, cared for at the Follow-up Clinic for Preterm Children of the Federal University of São Paulo, Brazil. The control group included 46 school-children born at term.
ED was more frequent in PTC (87%) than in TC (44%; P<.05). All 34 PTC with tracheal intubation at birth presented ED, showing a strong association between both. The variable was not included in the regression model. To analyze neonatal factors associated with ED in PTC, a model of logistic regression was adjusted. Malnutrition at term-corrected age increased the risk of ED in PTC 7.8 times. Opacity (white/cream) and hypoplasia (missing enamel) were frequent types of ED in this series. PTC and TC presented with high ED frequencies.
The frequencies of enamel defects were elevated in term and preterm children, but were higher in the latter. Tracheal intubation was strongly associated with enamel defects, and extrauterine growth restriction significantly increased the risk for enamel defects in preterm children.
本研究旨在比较足月儿(TC)和早产儿(PTC)全口乳牙列(CDD)中釉质缺陷(ED)的发生率,并分析与PTC中ED相关的新生儿因素。
研究组由45名PTC组成,在巴西圣保罗联邦大学早产儿随访诊所接受护理。对照组包括46名足月出生的学童。
PTC中ED的发生率(87%)高于TC(44%;P<0.05)。所有34名出生时接受气管插管的PTC均出现ED,表明两者之间存在强关联。该变量未纳入回归模型。为分析与PTC中ED相关的新生儿因素,调整了逻辑回归模型。足月校正年龄时的营养不良使PTC中ED的风险增加7.8倍。本系列中,透明度(白色/米色)和发育不全(釉质缺失)是常见的ED类型。PTC和TC的ED发生率都很高。
足月儿和早产儿的釉质缺陷发生率均升高,但后者更高。气管插管与釉质缺陷密切相关,宫外生长受限显著增加了早产儿发生釉质缺陷的风险。