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骨质疏松症:儿童牙科领域日益受到关注的问题。

Osteoporosis: an increasing concern in pediatric dentistry.

作者信息

da Fonseca Marcio A

机构信息

Law-Lewis professor and director of the graduate program, Department of Pediatric Dentistry, The Center for Pediatric Dentistry, University of Washington, Seattle, Washington, USA.

出版信息

Pediatr Dent. 2011 May-Jun;33(3):241-5.

PMID:21703077
Abstract

Increasing numbers of children are being affected by low bone density and osteoporosis. Bone fractures are the main reason for hospitalization between 10 and 14 years of age and, over the past 3 decades, there has been an increase in the incidence of fractures in children. Childhood factors such as lifestyle, diet, chronic illness, and medications have a vital short-term impact on bone health and a long-term effect on the achievement of peak bone mass, with the potential for morbidity in adulthood. The primary forms of osteoporosis consist of rare inherited conditions, but the secondary forms are becoming more common given that chronically ill children are surviving longer. This subject should be of interest to pediatric dentists, because low mineral density and osteoporosis, together with drugs used to treat them (eg, bisphosphonates), may cause adverse effects in the oral cavity. Furthermore, the pediatric dentist is an important health care professional to counsel patients about healthy lifestyles that can help prevent the condition from an early age.

摘要

越来越多的儿童受到低骨密度和骨质疏松症的影响。骨折是10至14岁儿童住院的主要原因,在过去30年中,儿童骨折的发病率有所上升。生活方式、饮食、慢性病和药物等儿童期因素对骨骼健康有至关重要的短期影响,并对达到峰值骨量有长期影响,有可能导致成年期发病。骨质疏松症的主要形式包括罕见的遗传疾病,但鉴于慢性病儿童的存活时间延长,继发性形式正变得越来越普遍。这个主题应该引起儿科牙医的兴趣,因为低矿物质密度和骨质疏松症,以及用于治疗它们的药物(如双膦酸盐)可能会在口腔中产生不良反应。此外,儿科牙医是重要的医疗保健专业人员,可就有助于从幼年预防该病的健康生活方式向患者提供咨询。

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Osteoporosis: an increasing concern in pediatric dentistry.骨质疏松症:儿童牙科领域日益受到关注的问题。
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PLoS One. 2015 Jan 22;10(1):e0115091. doi: 10.1371/journal.pone.0115091. eCollection 2015.
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Reference values of bone stiffness index and C-terminal telopeptide in healthy European children.健康欧洲儿童骨硬度指数和C端肽的参考值
Int J Obes (Lond). 2014 Sep;38 Suppl 2:S76-85. doi: 10.1038/ijo.2014.138.