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[疼痛与抑郁:常见关联的认知和行为中介因素]

[Pain and depression: cognitive and behavioural mediators of a frequent association].

作者信息

Radat F, Koleck M

机构信息

Centre douleur chronique, CHU Pellegrin, 33076 Bordeaux, France.

出版信息

Encephale. 2011 Jun;37(3):172-9. doi: 10.1016/j.encep.2010.08.013. Epub 2010 Oct 8.

DOI:10.1016/j.encep.2010.08.013
PMID:21703432
Abstract

LITERATURE FINDINGS

The comorbidity between chronic pain and depression is high: in the general population setting, the odds ratio for suffering from one of these disorders when suffering from the other is estimated around 2.5. For chronic pain patients consulting in pain clinics, the comorbidity rate reaches one third to half of the patients. For the International Association for the Study of Pain (IASP), pain consists in an emotional as well as a sensory dimension, both of them have to be assessed systematically. Likewise, affective disorders must be systematically depicted in chronic pain patients. The reasons for such comorbidity are complex and result from the conjunction of common risk factors (environmental and genetic vulnerability factors) and of a bidirectional causality. THE TRANSACTIONAL MODEL OF STRESS AND COPING OF LAZARUS ET FOLKMAN: The appraisal stress model (Lazarus and Folkman, 1984) offers an opportunity to understand how chronic pain can cause depression. Pain is conceptualized as a chronic stress. Its appraisal in terms of loss, injustice, incomprehensibility or changes (primary appraisal), and in terms of control (secondary evaluation) determine how the subject will cope with pain. Several personality traits as optimism, hardiness or internal locus of control play a protective role on these evaluations, whereas others (neuroticism, negative affectivity or external locus of control) are risk factors for depression. Low perceived social support is also related to depression. On the contrary, self-efficiency is linked with low levels of depression. Self-management therapies focus on increase of perceived control of pain by the patient in order to improve his/her motivation to change, and to let the patient become active in the management of his/her pain.

CONCLUSION

According to Lazarus and Folkman (1984), coping strategies are the constantly changing cognitive and behavioural efforts to manage specific external and/or internal demands that are appraised as taxing on or exceeding the resources of the person. Pain patients can use a wide variety of pain coping strategies: problem versus emotion focused strategies or cognitive versus behavioural strategies. Some of them are highly dysfunctional, such as catastrophizing (cognitive strategy) or avoidance (behavioural strategy). Their preferential use can lead to the development of a depressive episode. The "fear-avoidance model" (Vlayen, 2000) explains pain chronicization by a vicious circle that begins with the pain catastrophizing; this leads to fear of pain, which in turn leads to avoidance and finally to pain and depression. This is why some behavioural cognitive interventions focus on the reduction of catastrophizing and avoidance. Some functional pain coping strategies were identified: they are active strategies centred on problem resolution such as distraction, reinterpretation or ignorance of pain sensations, acceptance, and exercise and task persistence. New therapeutic interventions focus on the development of better coping strategies such as distraction, relaxation and acceptance.

摘要

文献研究结果

慢性疼痛与抑郁症之间的共病率很高:在普通人群中,患其中一种疾病时患另一种疾病的比值比估计约为2.5。在疼痛诊所就诊的慢性疼痛患者中,共病率达到患者总数的三分之一至一半。对于国际疼痛研究协会(IASP)而言,疼痛包括情感和感觉两个维度,必须对这两个维度进行系统评估。同样,必须对慢性疼痛患者的情感障碍进行系统描述。这种共病的原因很复杂,是由共同风险因素(环境和遗传易感性因素)以及双向因果关系共同导致的。拉扎勒斯和福克曼的压力与应对交互模型:评估压力模型(拉扎勒斯和福克曼,1984年)为理解慢性疼痛如何导致抑郁症提供了契机。疼痛被概念化为一种慢性压力。其在损失、不公正、不可理解或变化方面的评估(初级评估),以及在控制方面的评估(次级评估),决定了个体应对疼痛的方式。一些人格特质,如乐观、坚韧或内控点,在这些评估中起保护作用,而其他特质(神经质、消极情感或外控点)则是抑郁症的风险因素。感知到的社会支持较低也与抑郁症有关。相反,自我效能感与低水平的抑郁有关。自我管理疗法专注于增强患者对疼痛的感知控制,以提高其改变的动力,并让患者积极参与自身疼痛的管理。

结论

根据拉扎勒斯和福克曼(1984年)的观点,应对策略是为管理被评估为对个人资源造成负担或超出个人资源的特定外部和/或内部需求而不断变化的认知和行为努力。疼痛患者可以采用多种疼痛应对策略:问题聚焦与情绪聚焦策略,或认知与行为策略。其中一些策略功能失调性很强,例如灾难化思维(认知策略)或回避(行为策略)。优先使用这些策略可能导致抑郁发作。“恐惧 - 回避模型”(弗莱扬,2000年)通过一个恶性循环来解释疼痛慢性化,这个循环始于疼痛灾难化思维;这会导致对疼痛的恐惧,进而导致回避,最终导致疼痛和抑郁。这就是为什么一些行为认知干预专注于减少灾难化思维和回避行为。一些功能性疼痛应对策略已被确定:它们是以解决问题为中心的积极策略,如分散注意力、重新解读或忽略疼痛感觉、接受以及锻炼和坚持完成任务。新的治疗干预措施专注于开发更好的应对策略,如分散注意力、放松和接受。

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