Department of Psychiatry, School of Medicine, WPIC-BT 764, 3811 O'Hara St, Pittsburgh PA 15213, USA.
PM R. 2011 Jun;3(6 Suppl 1):S45-51. doi: 10.1016/j.pmrj.2011.05.007.
Cognitive impairment is a common sequela in acquired brain injury and one that predicts rehabilitation outcomes. There is emerging evidence that impairments in cognitive functions can be manipulated by both pharmacologic and nonpharmacologic interventions to improve rehabilitation outcomes. By using stroke as a model for acquired brain injury, we review the evidence that links cognitive impairment to poor rehabilitation outcomes and discuss possible mechanisms to explain this association. Furthermore, we examine nascent promising research that suggests that interventions that target cognitive impairments can lead to better rehabilitation outcomes.
认知障碍是获得性脑损伤的常见后遗症之一，也是预测康复效果的因素。越来越多的证据表明，认知功能的损伤可以通过药物和非药物干预来进行调整，以改善康复效果。我们以中风作为获得性脑损伤的模型，综述了认知障碍与康复效果不佳之间的关联证据，并探讨了可能的机制来解释这种关联。此外，我们还研究了一些有前途的新兴研究，这些研究表明，针对认知障碍的干预措施可以带来更好的康复效果。
