Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Rome, Italy.
Fertil Steril. 2011 Aug;96(2):374-8. doi: 10.1016/j.fertnstert.2011.05.078. Epub 2011 Jun 24.
To identify a possible marker of follicular depletion in relation to some histologic parameters of endometriotic cysts.
Prospective study.
Università Cattolica del Sacro Cuore, Operative Division of Endocrinological Gynecology.
PATIENT(S): Seventy-seven patients (aged 20-40 years) with endometrioma.
INTERVENTION(S): Patients underwent laparoscopic surgery for ovarian endometriosis.
MAIN OUTCOME MEASURE(S): After excision of the cyst wall, involuntarily removed follicles were correlated with age at surgery and with intrinsic histologic parameters of the specimen (thickness and composition of capsule; size of cyst).
RESULT(S): There was a statistically significant relationship between patient age and number of follicles in the histologic section, a statistically significant inverse relationship between size of cyst and number of follicles, and no significant correlation between thickness of the capsule and number of follicles. Fibroblastic-type capsule, most frequently found in younger patients, was associated with removal of a significantly higher number of follicles.
CONCLUSION(S): Our study suggests that patient age and cyst dimension are related to the histologic composition of the capsule, which is a marker of the aggressiveness of the cyst itself.
确定与子宫内膜异位囊肿的某些组织学参数相关的卵泡耗竭的可能标志物。
前瞻性研究。
圣心天主教大学，内分泌妇科手术科。
77 名患者（年龄 20-40 岁）患有卵巢子宫内膜异位症。
患者接受腹腔镜卵巢子宫内膜异位症手术。
切除囊肿壁后，将自发切除的卵泡与手术时的年龄以及标本的内在组织学参数（囊的厚度和组成；囊肿的大小）相关联。
患者年龄与组织切片中的卵泡数量之间存在统计学显著关系，囊肿大小与卵泡数量之间存在统计学显著负相关，囊厚度与卵泡数量之间无显著相关性。纤维母细胞型囊，最常发生在年轻患者中，与切除的卵泡数量明显增加相关。
我们的研究表明，患者年龄和囊肿尺寸与囊的组织学组成有关，这是囊本身侵袭性的标志物。
