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在零容忍时代预防导管相关尿路感染。

Preventing catheter-associated urinary tract infection in the zero-tolerance era.

机构信息

Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.

出版信息

Am J Infect Control. 2011 Dec;39(10):817-22. doi: 10.1016/j.ajic.2011.01.013. Epub 2011 Jun 25.

DOI:10.1016/j.ajic.2011.01.013
PMID:21704427
Abstract

BACKGROUND

Catheter-associated urinary tract infection (CAUTI) is one of the most common health care‒associated infections in the critical care setting.

METHODS

A quasi-experimental study involving multiple interventions to reduce the incidence of CAUTI was conducted in a medical-surgical intensive care unit (ICU) and in 2 step-down units (SDUs). Between June 2005 and December 2007 (phase 1), we implemented some Centers for Disease Control and Prevention‒recommended evidence-based practices. Between January 2008 and July 2010 (phase 2), we intervened to improve compliance with these practices at the same time that performance monitoring was being done at the bedside, and we implemented the Institute for Healthcare Improvement's bladder bundle for all ICU and SDU patients requiring urinary catheters.

RESULTS

There was a statistically significant reduction in the rate of CAUTI in the ICU, from 7.6 per 1,000 catheter-days (95% confidence interval [CI], 6.6-8.6) before the intervention to 5.0 per 1,000 catheter-days (95% CI, 4.2-5.8; P < .001) after the intervention. There also was a statistically significant reduction in the rate of CAUTI in the SDUs, from 15.3 per 1,000 catheter-days (95% CI, 13.9-16.6) before the intervention to 12.9 per 1,000 catheter-days (95% CI, 11.6-14.2) after the intervention (P = .014).

CONCLUSION

Our findings suggest that reducing CAUTI rates in the ICU setting is a complex process that involves multiple performance measures and interventions that can be applied to SDU settings as well.

摘要

背景

导管相关尿路感染(CAUTI)是重症监护病房中最常见的医疗保健相关感染之一。

方法

在一个内科重症监护病房(ICU)和两个过渡护理病房(SDU)中进行了一项涉及多种干预措施以降低 CAUTI 发生率的准实验研究。在 2005 年 6 月至 2007 年 12 月(第 1 阶段)期间,我们实施了一些疾病控制和预防中心推荐的基于证据的实践。在 2008 年 1 月至 2010 年 7 月(第 2 阶段)期间,我们干预以提高这些实践的依从性,同时在床边进行绩效监测,并为所有需要导尿管的 ICU 和 SDU 患者实施了医疗改进研究所的膀胱捆绑包。

结果

ICU 中 CAUTI 的发生率显著降低,从干预前的每 1000 个导管日 7.6 例(95%置信区间 [CI],6.6-8.6)降至干预后的每 1000 个导管日 5.0 例(95%CI,4.2-5.8;P <.001)。SDUs 中 CAUTI 的发生率也显著降低,从干预前的每 1000 个导管日 15.3 例(95%CI,13.9-16.6)降至干预后的每 1000 个导管日 12.9 例(95%CI,11.6-14.2)(P =.014)。

结论

我们的研究结果表明,降低 ICU 环境中的 CAUTI 发生率是一个复杂的过程,需要涉及多个绩效指标和干预措施,这些措施也可以应用于 SDU 环境。

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