Suppr超能文献

RAD 评分:一种简单的急性哮喘严重程度评分与更复杂的评分相比具有优势。

The RAD score: a simple acute asthma severity score compares favorably to more complex scores.

机构信息

Department of Pediatrics, Division of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

出版信息

Ann Allergy Asthma Immunol. 2011 Jul;107(1):22-8. doi: 10.1016/j.anai.2011.03.011. Epub 2011 Apr 22.

Abstract

BACKGROUND

Acute asthma severity scores facilitate assessment and implementation of timely and appropriate therapy for pediatric patients but are complex and challenging for clinicians to use at the bedside.

OBJECTIVE

To assess whether a simple, bedside acute asthma severity score comprising 3 standard clinical measures performs as well as more comprehensive asthma scores.

METHODS

We prospectively enrolled participants 5 to 17 years of age with acute asthma exacerbations. We recorded 3 asthma scores at baseline and after 2 hours of treatment: the Pediatric Asthma Severity Score (PASS), the Pediatric Respiratory Assessment Measure (PRAM), and the RAD score (Respiratory rate; Accessory muscle use; Decreased breath sounds). We assessed each score for criterion validity in predicting baseline percent forced expiratory volume in 1 second (%FEV(1)) and for responsiveness in predicting change of %FEV(1) after 2 hours of treatment using multiple linear regression models adjusted for age, race, sex, and Global Initiative for Asthma chronic control.

RESULTS

Of 536 participants included for analyses, median age was 8.8 years, 60% were male, and 58% were African American. The 3 acute asthma scores demonstrated similar criterion validity to explain variation of baseline %FEV(1) (R(2): 0.434 [PASS]; 0.462 [PRAM]; 0.426 [RAD]), but none demonstrated clinically significant responsiveness to change in %FEV(1) (R(2): 0.109 [PASS]; 0.106 [PRAM]; 0.139 [RAD]).

CONCLUSIONS

The RAD score, comprising 3 routinely measured bedside clinical parameters, is a simple and easily used instrument for assessing the severity of an acute asthma exacerbation and has comparable criterion validity and improved responsiveness when compared with 2 more complex acute asthma scores.

摘要

背景

急性哮喘严重程度评分有助于评估和实施儿科患者的及时和适当治疗,但对于临床医生来说,在床边使用这些评分非常复杂和具有挑战性。

目的

评估由 3 项标准临床测量组成的简单床边急性哮喘严重程度评分与更全面的哮喘评分表现相当。

方法

我们前瞻性纳入了 5 至 17 岁的急性哮喘加重患者。我们在基线和治疗 2 小时后记录了 3 项哮喘评分:小儿哮喘严重程度评分(PASS)、小儿呼吸评估量表(PRAM)和 RAD 评分(呼吸频率;辅助肌肉使用;呼吸音减弱)。我们使用多元线性回归模型评估了每个评分在预测基线 1 秒用力呼气量百分比(%FEV(1))方面的标准有效性,并评估了在调整年龄、种族、性别和全球哮喘倡议慢性控制后,2 小时治疗后 %FEV(1)变化的反应性。

结果

在纳入分析的 536 名参与者中,中位年龄为 8.8 岁,60%为男性,58%为非裔美国人。这 3 项急性哮喘评分在解释基线 %FEV(1)变异方面具有相似的标准有效性(R(2):0.434 [PASS];0.462 [PRAM];0.426 [RAD]),但没有一项评分在 %FEV(1)变化方面表现出明显的临床反应性(R(2):0.109 [PASS];0.106 [PRAM];0.139 [RAD])。

结论

RAD 评分由 3 项常规床边临床参数组成,是一种简单易用的评估急性哮喘发作严重程度的工具,与 2 种更复杂的急性哮喘评分相比,它具有相似的标准有效性和改善的反应性。

相似文献

引用本文的文献

本文引用的文献

2
Clinical measures associated with FEV1 in persons with asthma requiring hospital admission.
Am J Emerg Med. 2007 May;25(4):425-9. doi: 10.1016/j.ajem.2006.09.006.
4
Review: a gentle introduction to imputation of missing values.综述:缺失值插补的简要介绍
J Clin Epidemiol. 2006 Oct;59(10):1087-91. doi: 10.1016/j.jclinepi.2006.01.014. Epub 2006 Jul 11.
8
Acute severe asthma.急性重症哮喘
Am J Respir Crit Care Med. 2003 Oct 1;168(7):740-59. doi: 10.1164/rccm.200208-902SO.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验