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颅内静脉窦支架置入术治疗良性颅内高压:临床适应证、技术及初步结果。

Intracranial venous sinus stenting for benign intracranial hypertension: clinical indications, technique, and preliminary results.

机构信息

Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.

出版信息

World Neurosurg. 2011 May-Jun;75(5-6):648-52; discussion 592-5. doi: 10.1016/j.wneu.2010.11.012.

Abstract

OBJECTIVE

The cause of pseudotumor cerebri, or benign intracranial hypertension (BIH), is controversial. We report our results from 18 cases of venous sinus stenting (VSS), the largest series in the literature, with specific focus on the rate of technical success, amelioration of the subjective symptom of headache, attendant complications, and radiographic patency on follow-up.

METHODS

Review of our prospectively maintained database identified 18 patients who had undergone 19 VSS procedures for the placement of 30 stents in the past 2.5 years. Indications for treatment included a clinical diagnosis of BIH with venographic demonstration of stenosis.

RESULTS

VSS was technically successful in all patients (100%). No patient suffered a permanent complication. Three patients were lost to follow-up. The remaining 15 patients were followed clinically and asked to rate their headache severity on a scale of 1 to 10 both before and after VSS. Overall, 12 patients (80%) qualified their headaches as better after VSS, two stated that they were the same, and one patient said that they were worse. Of 14 patients who underwent follow-up angiography, all demonstrated normal patency of the stented segments. In one of these patients, stenosis was detected on follow-up in the unstented segment of the sigmoid sinus and jugular bulb.

CONCLUSIONS

VSS is highly effective (80%) in ameliorating headache associated with BIH. The procedure is associated with a high rate of technical success (100%), a low rate of permanent complications (0), and a high rate of stent patency on follow-up angiography (100%).

摘要

目的

假性脑瘤或良性颅内高压(BIH)的病因仍存在争议。我们报告了 18 例静脉窦支架置入术(VSS)的结果,这是文献中最大的系列,特别关注技术成功率、头痛主观症状的改善、伴随的并发症以及随访时的放射影像学通畅性。

方法

回顾性分析我们前瞻性维护的数据库,确定了过去 2.5 年内 18 例接受 19 例 VSS 治疗的患者,共置入 30 个支架。治疗的适应证包括临床诊断为 BIH 并伴有静脉造影显示狭窄。

结果

所有患者(100%)的 VSS 技术均成功。无患者发生永久性并发症。3 例患者失访。其余 15 例患者进行了临床随访,并在 VSS 前后分别用 1 到 10 的量表对其头痛严重程度进行评分。总体而言,12 例患者(80%)认为 VSS 后头痛减轻,2 例患者表示相同,1 例患者表示更严重。14 例接受随访血管造影的患者中,所有支架段均显示正常通畅。其中 1 例患者在随访时发现未支架的乙状窦和颈静脉球段存在狭窄。

结论

VSS 治疗 BIH 相关头痛非常有效(80%)。该手术技术成功率高(100%),永久性并发症发生率低(0%),随访血管造影显示支架通畅率高(100%)。

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