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解剖后腹腔镜肾上腺切除术治疗>5cm 选定肾上腺肿瘤:我们的技术和经验。

Anatomic retroperitoneoscopic adrenalectomy for selected adrenal tumors >5 cm: our technique and experience.

机构信息

Department of Urology, China PLA General Hospital, Beijing, China.

出版信息

Urology. 2011 Aug;78(2):348-52. doi: 10.1016/j.urology.2011.02.035. Epub 2011 Jun 25.

Abstract

OBJECTIVES

To introduce our experience in using anatomic retroperitoneoscopic adrenalectomy (ARA) for adrenal tumors >5 cm and evaluate this procedure's safety and efficiency.

METHODS

Of the 1400 ARAs performed in the past 8 years, 110 were performed on patients who had adrenal tumors with a diameter >5 cm. The perioperative indexes of these patients were retrospectively collected and analyzed.

RESULTS

The mean tumor size on postoperative pathologic examination was 7.2 ± 2.1 cm (range 5-14). Only 1 patient with right-sided adrenal pheochromocytoma (7.8 cm diameter) required conversion to open surgery owing to the tumor's severe adhesions to the liver and inferior vena cava. The mean operative time and evaluated blood loss was 70.8 ± 18.6 minutes and 81.3 ± 46.1 mL, respectively. The average postoperative interval to oral intake and drainage withdrawal was 2.1 and 2.2 days, respectively. No patient died during the operation. Major intraoperative complication (ie, injury to the vena cava) occurred in 1 patient, necessitating open surgery. Minor complications during the perioperative period occurred in 10 patients (9.1%).

CONCLUSIONS

When performed by experienced surgeons, ARA is a safe and feasible procedure for large adrenal masses with a diameter >7 cm; however, this procedure results in a longer operation time and greater blood loss compared with ARA performed on smaller masses. Open surgery is indicated when the tumor adheres to, or has infiltrated, the surrounding tissues.

摘要

目的

介绍我们在应用解剖后腹腔镜肾上腺切除术(ARA)治疗直径>5cm 肾上腺肿瘤方面的经验,并评估该术式的安全性和有效性。

方法

在过去 8 年中,我们共完成了 1400 例 ARA,其中 110 例患者的肾上腺肿瘤直径>5cm。回顾性收集并分析这些患者的围手术期指标。

结果

术后病理检查示肿瘤平均直径为 7.2±2.1cm(5-14cm)。仅 1 例右侧肾上腺嗜铬细胞瘤(直径 7.8cm)患者因肿瘤与肝和下腔静脉严重粘连而转为开放手术。手术时间和评估失血量的平均值分别为 70.8±18.6 分钟和 81.3±46.1ml。术后开始经口进食和拔除引流管的平均时间分别为 2.1 天和 2.2 天。术中无患者死亡。1 例患者发生主要并发症(即下腔静脉损伤),需行开放手术。10 例患者(9.1%)在围手术期出现轻微并发症。

结论

对于直径>7cm 的大肾上腺肿块,经验丰富的外科医生施行 ARA 是安全可行的,但与治疗较小肿块的 ARA 相比,该术式的手术时间更长,失血量更大。当肿瘤与周围组织粘连或浸润时,应选择开放手术。

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