活体证据表明，光调制的视网膜双极细胞产生尖峰。
In vivo evidence that retinal bipolar cells generate spikes modulated by light.
机构信息
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK.
出版信息
Nat Neurosci. 2011 Jun 26;14(8):951-2. doi: 10.1038/nn.2841.
Abstract
Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.
摘要
视网膜双极细胞被认为对光产生纯粹的分级反应。为了验证这一观点，我们在活体斑马鱼中对突触前钙瞬变进行了成像。我们发现，ON、OFF、瞬态和持续双极细胞都能够产生快速的“全有或全无”钙瞬变，这种钙瞬变可被视觉刺激调节。
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