Department of Metallurgy and Ceramics Science, Tokyo Institute of Technology, O-okayama 2-12-1, Meguro-ku, Tokyo 152-8550, Japan.
Chem Commun (Camb). 2011 Aug 7;47(29):8430-2. doi: 10.1039/c1cc12058a. Epub 2011 Jun 25.
Folic acid (FA) was immobilized on Eu(3+)-doped nanoporous silica spheres (Eu:NPSs) through mediation of the 3-aminopropyltriethoxysilane adlayer. The ordered nanopores of Eu:NPS were preserved by the immobilization. The FA-immobilized Eu:NPSs showed the characteristic photoluminescence peak due to interactions between the FA molecules and Eu(3+) ions, and highly dispersed stability in phosphate buffered saline.
叶酸（FA）通过 3-氨丙基三乙氧基硅烷的中间层固定在 Eu（3+）掺杂的纳米多孔硅球（Eu：NPSs）上。Eu：NPS 的有序纳米孔通过固定化得以保留。固定化的 FA-Eu：NPSs 显示出由于 FA 分子与 Eu（3+）离子之间的相互作用而产生的特征荧光峰，并在磷酸盐缓冲盐水中具有高度分散的稳定性。
