Mizobuchi Keiko, Takahasi Nobuyoshi, Ajima Akiko
Department of Neurology, Asahi Neurology and Rehabilitation Hospital.
Rinsho Shinkeigaku. 2011 May;51(5):350-3. doi: 10.5692/clinicalneurol.51.350.
A 65 year-old man showed bilateral, but more marked on the right, instinctive grasp reaction, utilization and imitation behavior after a right parietotemporal lobe infarction. Attention disturbance, left unilateral spatial neglect, and constructional disturbance were also observed. Fluid attenuated inversion recovery (FLAIR) MRI revealed high intensity lesions over the right parietotemporal cortex and white matter. Magnetic resonance angiography showed occlusion of the right internal carotid artery, and ultrasonography revealed left moderate internal carotid artery stenosis. Utilization and imitation behavior is usually attributed to a frontal lesion, rarely to a basal ganglionic or thalamic lesion, but not to a parietotemporal lesion. In this patient, the utilization and imitation behavior was thought to be attributed to right frontal lobe dysfunction without apparent MRI abnormalities, supposedly because of the right internal carotid artery occlusion in addition to the right parietal lobe infarction, both of which are thought to suppress the executive center in the left parietal lobe.
一名65岁男性在右侧顶颞叶梗死之后出现双侧本能握持反应、运用和模仿行为,但右侧更为明显。同时还观察到注意力障碍、左侧单侧空间忽视和结构性障碍。液体衰减反转恢复(FLAIR)磁共振成像显示右侧顶颞叶皮质和白质有高强度病变。磁共振血管造影显示右侧颈内动脉闭塞,超声检查显示左侧颈内动脉中度狭窄。运用和模仿行为通常归因于额叶病变,很少归因于基底神经节或丘脑病变,而非顶颞叶病变。在该患者中,运用和模仿行为被认为归因于右侧额叶功能障碍,磁共振成像未显示明显异常,推测是由于右侧颈内动脉闭塞以及右侧顶叶梗死,这两者均被认为抑制了左侧顶叶的执行中枢。