Tanaka Yosuke, Sasaki Yuko, Wada Akihito, Anzai Momoko, Akita Hironobu
Department of Clinical Laboratory, St Marianna University School of Medicine, Yokohama City Seibu Hospital.
Kansenshogaku Zasshi. 2011 May;85(3):275-9. doi: 10.11150/kansenshogakuzasshi.85.275.
A 36-year-old woman undergoing a myomectomy developed postoperative surgical-saite peritonitis and hematoma. Eight days postoperatively, she developed a 38 degrees C-plus fever and accumulated ascites, with fever unchanged despite antimicrobial beta-lactams therapy. Following transvaginal ascitic drainage, her fever disappeared. Recurrent 38 degrees C fever and inflammation were cured by clindamycin of 1.2 g/day. M. hominis detected from ascites drainage was considered the primary causative organism. Nongenito-urinary M. hominis infection is often difficult to detect, as in our case. Gram staining, for example, is not useful in ascertaining small organisms such as Mycoplasma spp. having no cell walls to stain. M. hominis grows slowly, requiring over three days to form colonies on blood agar plates, requiring time to identify pathogens. We report case showing the importance of suspecting M. hominis of causing gynecological surgical-site infection. When common bacterial pathogen cultures remain negative and when empiric beta-lactam antibiotic treatment is ineffective, M. hominis should be suspected. In conclusion, M. hominis should be considered a causative following myomectomy resection.
一名接受子宫肌瘤切除术的36岁女性术后出现手术部位腹膜炎和血肿。术后第8天,她体温升至38摄氏度以上,并出现腹水积聚,尽管使用了β-内酰胺类抗菌药物治疗,体温仍未下降。经阴道进行腹水引流后,她的发热症状消失。每日1.2克克林霉素治愈了反复出现的38摄氏度发热和炎症。从腹水引流液中检测出的人型支原体被认为是主要病原体。如我们的病例所示,非泌尿生殖道的人型支原体感染往往难以检测。例如,革兰氏染色对于确定像支原体属这样没有细胞壁可供染色的小生物体并无用处。人型支原体生长缓慢,在血琼脂平板上需要超过三天才能形成菌落,因此需要时间来鉴定病原体。我们报告了这一病例,显示怀疑人型支原体导致妇科手术部位感染的重要性。当常见细菌病原体培养结果为阴性且经验性β-内酰胺抗生素治疗无效时,应怀疑是人型支原体感染。总之,子宫肌瘤切除术后应考虑人型支原体为病原体。