Tohyama Kaoru
Department of Laboratory Medicine, Kawasaki Medical School, Kurashiki 701-0192, Japan.
Rinsho Byori. 2011 May;59(5):502-3.
The revised WHO classification of tumors of hematopoietic and lymphoid tissues (4th edition) was published in 2008. A number of information from molecular biology was introduced, new patterns of classification were proposed, and specific molecular diagnostics and molecular-targeting therapy were introduced in a part of these diseases. In this symposium, four remarkable points of the WHO-2008 classification (myeloproliferative neoplasms and JAK2 mutation, approaches to hypereosinophilic syndromes, morphology of myelodysplastic syndromes, and varied classification of lymphoid malignancies) were presented by the expert speakers, and the better understanding of the revised classification is warranted.
世界卫生组织造血与淋巴组织肿瘤分类(第4版)修订版于2008年发布。引入了许多来自分子生物学的信息,提出了新的分类模式,并在部分此类疾病中引入了特定的分子诊断和分子靶向治疗。在本次研讨会上,专家演讲者介绍了WHO-2008分类的四个显著要点(骨髓增殖性肿瘤与JAK2突变、高嗜酸性粒细胞综合征的处理方法、骨髓增生异常综合征的形态学以及淋巴系统恶性肿瘤的多样分类),有必要更好地理解这一修订后的分类。