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The 2010 Philip S. Portoghese Medicinal Chemistry Lectureship: addressing the "core issue" in the design of estrogen receptor ligands.

作者信息

Katzenellenbogen John A

机构信息

Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States.

出版信息

J Med Chem. 2011 Aug 11;54(15):5271-82. doi: 10.1021/jm200801h. Epub 2011 Jul 11.

DOI:10.1021/jm200801h
PMID:21707083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3150643/
Abstract
摘要

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Cell. 2011 May 13;145(4):584-95. doi: 10.1016/j.cell.2011.03.050.
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Structure of estradiol metal chelate and estrogen receptor complex: the basis for designing a new class of selective estrogen receptor modulators.雌二醇金属螯合物和雌激素受体复合物的结构:设计新型选择性雌激素受体调节剂的基础。
J Med Chem. 2011 May 26;54(10):3575-80. doi: 10.1021/jm200192y. Epub 2011 Apr 19.
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Synthesis and investigations on the oxidative degradation of C3/C5-alkyl-1,2,4-triarylpyrroles as ligands for the estrogen receptor.C3/C5-烷基-1,2,4-三芳基吡咯作为雌激素受体配体的氧化降解合成与研究。
ChemMedChem. 2011 May 2;6(5):794-803. doi: 10.1002/cmdc.201000537. Epub 2011 Mar 17.
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Estrogen receptors: therapies targeted to receptor subtypes.雌激素受体:针对受体亚型的治疗方法。
Clin Pharmacol Ther. 2011 Jan;89(1):44-55. doi: 10.1038/clpt.2010.226. Epub 2010 Dec 1.
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