Department of Chemistry, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.
Org Lett. 2011 Aug 5;13(15):4000-3. doi: 10.1021/ol201515c. Epub 2011 Jun 28.
A recently discovered anion receptor is jointed by three related macrocycles differing in the number of glycoluril units and type of substitution. The synthesis is carried out in nonpolar solvents compared to aqueous media used in the case of the original macrocycle. The size of macrocycle is controlled by a template. A hexameric macrocycle with benzyl substitution binds halide anions with an affinity exceeding 10(9) M(-1) while a tetrameric analog does not bind any of the investigated anions.
最近发现的阴离子受体由三个相关的大环组成，这些大环在三嗪环单元数量和取代基类型上有所不同。与原始大环在水相介质中进行的合成相比，该合成是在非极性溶剂中进行的。大环的大小由模板控制。具有苄基取代基的六元大环与卤化物阴离子的亲和力超过 10(9) M(-1)，而四元类似物则不与任何研究的阴离子结合。
