Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica-Voda Alley, Iasi 700487, Romania.
Nat Prod Res. 2011 Oct;25(17):1657-61. doi: 10.1080/14786419.2010.521502. Epub 2011 Jun 27.
The study reported here presents a comparative screening of three medicinal plants including oregano (Origanum vulgare L.), lavender (Lavandula angustifolia) and lemon balm (Melissa officinalis) having the same geographical origin, the Southeast region of Romania, and growing in the same natural conditions. The contents of total phenolics and total flavonoids for the extracts of these were determined. Furthermore, the total antioxidant capacity was also evaluated. It was found that Origanum vulgare and Melissa officinalis extracts present the most effective antioxidant capacity in scavenging DPPH radicals, while Lavandula angustifolia is less active. High performance liquid chromatography-mass spectrometry analysis was used to identify the components of extracts. Major phenolic acids identified in the analysed species were ferulic, rosmarinic, p-coumaric and caffeic, while predominant flavonoids were quercetin, apigenin kaempherol, which were present as glucosides.
本研究对三种药用植物(牛至(Origanum vulgare L.)、薰衣草(Lavandula angustifolia)和柠檬香脂(Melissa officinalis))进行了比较筛选,这些植物具有相同的地理起源(罗马尼亚东南部)和相同的自然生长条件。测定了这些提取物中总酚和总类黄酮的含量。此外,还评估了总抗氧化能力。结果表明,牛至和柠檬香脂提取物在清除 DPPH 自由基方面具有最强的抗氧化能力,而薰衣草的活性较低。采用高效液相色谱-质谱联用技术分析提取物的成分。在分析的物种中鉴定出的主要酚酸为阿魏酸、迷迭香酸、对香豆酸和咖啡酸,而主要的类黄酮为槲皮素、芹菜素、山奈酚,它们均以糖苷的形式存在。