Council of Scientific and Industrial Research-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata-700 032, India.
Anticancer Agents Med Chem. 2012 Jan;12(1):49-75. doi: 10.2174/187152012798764697.
Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.
天然产物是抗癌先导分子的重要来源。许多成功的抗癌药物都是天然产物或其类似物。还有更多的正在临床试验中。本综述重点介绍了 2005 年至 2010 年间报道的来自印度陆地植物的极性和非极性提取物、半纯化馏分和纯分子的化学预防和抗癌活性，强调了纯分子的可能作用机制。
