Medical Research Council Laboratories, Fajara, The Gambia.
Trop Med Int Health. 2011 Oct;16(10):1314-25. doi: 10.1111/j.1365-3156.2011.02809.x. Epub 2011 Jun 24.
To describe how, through a DSS in a rural area of The Gambia, it has been possible to measure substantial reductions in child mortality rates and how we investigated whether the decline paralleled the registered fall in malaria incidence in the country.
Demographic surveillance data spanning 19.5 years (1 April 1989-30 September 2008) from 42 villages around the town of Farafenni, The Gambia, were used to estimate childhood mortality rates for neonatal, infant, child (1-4 years) and under-5 age groups. Data were presented in five a priori defined time periods, and annual rates per 1000 live births were derived from Kaplan-Meier survival probabilities.
From 1989-1992 to 2004-2008, under-5 mortality declined by 56% (95% CI: 48-63%), from 165 (95% CI: 151-181) per 1000 live births to 74 (95% CI: 65-84) per 1000 live births. In 1- to 4-year-olds, mortality during the period 2004-2008 was 69% (95% CI: 60-76%) less than in 1989-1992. The corresponding mortality decline in infants was 39% (95% CI: 23-52%); in neonates, it was 38% (95% CI: 13-66%). The derived annual under-5 mortality rates declined from 159 per 1000 live births in 1990 to 45 per 1000 live births in 2008, thus implying an attainment of MDG4 seven years in advance of the target year of 2015.
Achieving MDG4 is possible in poor, rural areas of Africa through widespread deployment of relatively simple measures that improve child survival, such as immunisation and effective malaria control.
描述在冈比亚农村地区的决策支持系统(DSS)如何实现大幅降低儿童死亡率,并调查下降趋势是否与该国疟疾发病率的下降相吻合。
使用来自冈比亚法非尼镇周围 42 个村庄的 19.5 年(1989 年 4 月 1 日至 2008 年 9 月 30 日)的人口监测数据,估计新生儿、婴儿、儿童(1-4 岁)和 5 岁以下儿童死亡率。数据以五个预先定义的时间段呈现,每年每 1000 例活产的死亡率是根据 Kaplan-Meier 生存概率得出的。
从 1989-1992 年到 2004-2008 年,5 岁以下儿童死亡率下降了 56%(95%CI:48-63%),从每 1000 例活产 165 例(95%CI:151-181 例)降至每 1000 例活产 74 例(95%CI:65-84 例)。在 1-4 岁儿童中,2004-2008 年期间的死亡率比 1989-1992 年期间低 69%(95%CI:60-76%)。同期婴儿死亡率下降 39%(95%CI:23-52%);新生儿死亡率下降 38%(95%CI:13-66%)。由此得出的每年 5 岁以下儿童死亡率从 1990 年的每 1000 例活产 159 例降至 2008 年的每 1000 例活产 45 例,这意味着在 2015 年目标年份之前提前七年实现了千年发展目标 4。
在非洲贫穷的农村地区,通过广泛部署改善儿童生存的相对简单措施,如免疫接种和有效控制疟疾,可以实现千年发展目标 4。