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经导管动脉栓塞术治疗肾血管平滑肌脂肪瘤:15 年经验的演变。

Transcatheter arterial embolization as therapy of renal angiomyolipomas: the evolution in 15 years of experience.

机构信息

University of Athens, Aretaieion Hospital, Radiology Department, Greece.

出版信息

Eur J Radiol. 2012 Sep;81(9):2308-12. doi: 10.1016/j.ejrad.2011.06.003. Epub 2011 Jun 25.

Abstract

OBJECTIVE

This study aims at presenting the evolution of the embolization technique in treating renal angiomyolipomas (AMLs) either diagnosed in patients with acute bleeding or discovered accidentally.

METHODS

Ten patients with renal AMLs have been through thirteen selective transcatheter arterial embolizations for 15 years. Two patients had tuberous sclerosis complex (TSC) with bilateral tumors and were embolized twice. Four embolic materials were employed: PVA particles, Gianturco coils, microspheres and microcoils. Catheterization was achieved by means of 5F Cobra 2 catheters and coaxial microcatheter systems.

RESULTS

On an emergency basis, embolization was a first-line treatment. In one case, surgery was necessary; in two patients, a second embolization was performed. When treatment was preventive, a single embolization proved to be sufficient, as well. There was no significant deterioration of the serum creatinine levels in the post-embolization period.

CONCLUSION

Selective arterial embolization is a rather safe and effective technique to treat AMLs both urgently and preventively. Different embolic materials can be employed. Microspheres and microcatheters stand for new promising materials.

摘要

目的

本研究旨在介绍栓塞技术在治疗因急性出血而诊断或意外发现的肾血管平滑肌脂肪瘤(AML)的演变。

方法

15 年来,10 例肾 AML 患者接受了 13 次选择性经导管动脉栓塞治疗。2 例患者患有结节性硬化症(TSC),且双侧均有肿瘤,接受了 2 次栓塞治疗。共使用了 4 种栓塞材料:PVA 颗粒、Gianturco 线圈、微球和微导管。通过 5F Cobra 2 导管和同轴微导管系统进行导管插入。

结果

在紧急情况下,栓塞是一线治疗方法。1 例患者需要手术治疗;2 例患者进行了第二次栓塞治疗。预防性治疗时,单次栓塞也足够有效。栓塞后血清肌酐水平无明显恶化。

结论

选择性动脉栓塞术是一种安全有效的治疗 AML 的方法,无论是紧急治疗还是预防性治疗。可以使用不同的栓塞材料。微球和微导管是有前途的新型材料。

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