Division of Obstetrics and Gynecology, Kanagawa Children's Medical Center, Yokohama, Japan.
Fetal Diagn Ther. 2011;30(3):184-8. doi: 10.1159/000327542. Epub 2011 Jun 25.
Unlike gastroschisis, congenital omphalocele is often associated with other anomalies and is frequently complicated by polyhydramnios. We examined the relationships between polyhydramnios, pregnancy outcome and fetal prognosis.
Clinical data from cases diagnosed antenatally with congenital omphalocele from 1993 to 2006 were analyzed retrospectively.
Fifty-two cases were diagnosed antenatally with congenital omphalocele, and 38 of these pregnancies resulted in delivered infants. Of these 38 pregnancies, 55.3% were preterm births before 37 weeks of gestation. The mean birth weight was 2,148 g (n = 38). Associated anomalies were recognized in 29 cases (76.3%), including 13 cases (34.2%) of chromosomal aberrations. There were 2 cases of trisomy 13, 10 cases of trisomy 18 and 1 case of trisomy 21. Polyhydramnios was detected in 14 cases (36.8%), and other anomalies were present in all of these cases.
For antenatal evaluation in cases of congenital omphalocele, it is important to examine the fetus for associated anomalies or underlying disease, especially when polyhydramnios is detected.
与腹裂不同，先天性脐膨出常伴有其他畸形，且常并发羊水过多。我们研究了羊水过多、妊娠结局和胎儿预后之间的关系。
回顾性分析了 1993 年至 2006 年间产前诊断为先天性脐膨出的病例的临床资料。
52 例产前诊断为先天性脐膨出，其中 38 例分娩。这 38 例中，55.3%为 37 周前早产。平均出生体重为 2148g（n=38）。29 例（76.3%）识别出相关畸形，包括 13 例（34.2%）染色体异常。有 2 例 13 三体，10 例 18 三体和 1 例 21 三体。14 例（36.8%）检测到羊水过多，所有这些病例均存在其他异常。
对于先天性脐膨出的产前评估，重要的是要检查胎儿是否存在相关畸形或潜在疾病，尤其是在检测到羊水过多时。
