2007年澳大利亚一株H3N8马流感病毒的分离与鉴定

Isolation and characterisation of an H3N8 equine influenza virus in Australia, 2007.

作者信息

Watson J, Halpin K, Selleck P, Axell A, Bruce K, Hansson E, Hammond J, Daniels P, Jeggo M

机构信息

CSIRO Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia.

出版信息

Aust Vet J. 2011 Jul;89 Suppl 1:35-7. doi: 10.1111/j.1751-0813.2011.00738.x.

DOI:10.1111/j.1751-0813.2011.00738.x

PMID:21711282

Abstract

Before 2007, equine influenza had never been diagnosed in Australia. On 22 August 2007, infection was confirmed in horses at Eastern Creek Animal Quarantine Station near Sydney. The virus subsequently isolated (A/equine/Sydney/2888-8/2007) was confirmed by sequence analysis of the haemagglutinin (HA) gene as an H3 virus of the variant American Florida lineage that is now referred to as Clade 1. The HA sequence of the virus was identical to that of a virus isolated from a contemporaneous outbreak in Japan and showed high homology to viruses circulating in North America.

摘要

2007年之前，澳大利亚从未诊断出马流感。2007年8月22日，悉尼附近的伊斯特克里克动物检疫站的马匹被确诊感染。随后分离出的病毒（A/equine/Sydney/2888-8/2007）经血凝素（HA）基因序列分析，确认为变异型美国佛罗里达谱系的H3病毒，现称为进化枝1。该病毒的HA序列与从日本同期疫情中分离出的一种病毒相同，与在北美传播的病毒具有高度同源性。