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今日毒理学:你现在需要了解的内容。

Toxicology today: what you need to know now.

作者信息

Lam Simon W, Engebretsen Kristin M, Bauer Seth R

机构信息

Cleveland Clinic, Department of Pharmacy, Cleveland, OH 44195, USA.

出版信息

J Pharm Pract. 2011 Apr;24(2):174-88. doi: 10.1177/0897190011400552. Epub 2011 Mar 14.

Abstract

Clinicians are frequently confronted with toxicological emergencies and challenged with the task of correctly identifying the possible agents involved and providing appropriate treatments. In this review article, we describe the epidemiology of overdoses, provide a practical approach to the recognition and diagnosis of classic toxidromes, and discuss the initial management strategies that should be considered in all overdoses. In addition, we evaluate some of the most common agents involved in poisonings and present their respective treatments. Recognition of toxidromes with knowledge of indications for antidotes and their limitations for treating overdoses is crucial for the acute care of poisoned patients.

摘要

临床医生经常面临中毒急症,并面临正确识别可能涉及的药物并提供适当治疗的任务挑战。在这篇综述文章中,我们描述了过量用药的流行病学,提供了识别和诊断典型中毒综合征的实用方法,并讨论了所有过量用药情况下应考虑的初始管理策略。此外,我们评估了一些中毒中最常见的药物,并介绍了它们各自的治疗方法。了解解毒剂的适应症及其治疗过量用药的局限性来识别中毒综合征,对于中毒患者的急性护理至关重要。

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