Mallows James, Chan Betty, Graudins Andis
Department of Emergency Medicine, Nepean Hospital, Kingswood, New South Wales, Australia.
Emerg Med Australas. 2005 Oct-Dec;17(5-6):511-9. doi: 10.1111/j.1742-6723.2005.00784.x.
The Monthly Index of Medical Specialties (MIMS) contains Therapeutic Goods Administration-approved product information supplied by manufacturers. It is widely used by health-care professionals but is not specifically designed as a toxicology reference.
To determine how widespread the use of MIMS is as a toxicology reference. To evaluate the quality of poisoning management advice it contains.
First, a survey of 500 consecutive calls to the NSW Poison Information Centre (PIC) was undertaken asking health-care workers which toxicology references were consulted prior to calling and which references they would use if the PIC were not available. Second, a consensus opinion for poisoning management was obtained, for 25 medications which are either commonly involved in poisoning or potentially life-threatening in overdose, by review of 5 current toxicology references for contraindicated treatments, ineffective treatments and specific recommended treatments and antidotes. MIMS poisoning management advice was then compared with this toxicology consensus opinion.
In total, 276 doctors and 222 nurses were surveyed. Prior to calling the PIC 22.8% of doctors and 6.8% of nurses consulted MIMS. In total, 25.7% of doctors and 39.6% nurses stated they would use the MIMS for poisoning management advice if the PIC were not available. For the 25 drugs assessed, 14 contained inaccurate poisoning management: 1 recommended ineffective treatments and 14 omitted specific treatments or antidotes.
The MIMS is often used as a toxicology reference by physicians prior to calling the PIC. It contains a number of significant inaccuracies pertaining to management of poisonings and should not be used as a primary reference for poisoning advice.
《医学专科月度索引》（MIMS）包含制造商提供的治疗用品管理局批准的产品信息。它被医疗保健专业人员广泛使用，但并非专门设计用作毒理学参考资料。
确定MIMS作为毒理学参考资料的使用普及程度。评估其所含中毒管理建议的质量。
首先，对新南威尔士州中毒信息中心（PIC）连续接到的500个电话进行了调查，询问医护人员在打电话之前查阅了哪些毒理学参考资料，以及如果无法联系到PIC他们会使用哪些参考资料。其次，通过查阅5份当前的毒理学参考资料，获取了关于25种常用于中毒或过量服用时有潜在生命危险的药物的中毒管理共识意见，内容涉及禁忌治疗、无效治疗以及具体推荐的治疗方法和解毒剂。然后将MIMS的中毒管理建议与该毒理学共识意见进行比较。
总共调查了276名医生和222名护士。在致电PIC之前，22.8%的医生和6.8%的护士查阅了MIMS。总计，25.7%的医生和39.6%的护士表示，如果无法联系到PIC，他们会使用MIMS获取中毒管理建议。对于所评估的25种药物，14种药物的中毒管理内容不准确：1种推荐了无效治疗方法，14种遗漏了具体治疗方法或解毒剂。
医生在致电PIC之前经常将MIMS用作毒理学参考资料。它在中毒管理方面存在一些重大不准确之处，不应作为中毒建议的主要参考资料。
