Blanc F, Ngoc-Huyen V, Warnet J M, Claude J R, Truhaut R
Toxicol Eur Res. 1978 Jan;1(1):13-21.
Aramite has been administered to male rats by oral route during 56 weeks at a daily dose of 400 mg/kg. There was a decrease of the body weight and several animals died. Liver hypertrophy was observed with neoplasic proliferation of parenchymatous cells and cholangiocarcinoma.
已对雄性大鼠经口给予阿拉米特,持续56周,每日剂量为400毫克/千克。出现体重下降,并有几只动物死亡。观察到肝脏肥大,伴有实质细胞的肿瘤性增殖和胆管癌。