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球囊小肠镜在神经纤维瘤病相关小肠胃肠道间质瘤术前诊断中的应用：一例报告

Use of balloon enteroscopy in preoperative diagnosis of neurofibromatosis-associated gastrointestinal stromal tumours of the small bowel: a case report.

作者信息

Takakura Kazuki, Kajihara Mikio, Sasaki Shigemasa, Nagano Tomohisa, Ohta Arihito, Ikegami Masahiro, Eto Ken, Kashiwagi Hideyuki, Yanaga Katsuhiko, Arihiro Seiji, Kato Tomohiro, Tajiri Hisao

出版信息

Case Rep Gastroenterol. 2011 May;5(2):308-14. doi: 10.1159/000329171. Epub 2011 May 28.

DOI:10.1159/000329171
PMID:21712945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3124322/
Abstract

Neurofibromatosis type I (NF1) is one of the most common inheritable disorders and is associated with an increased risk of gastrointestinal stromal tumours (GISTs). However, the predominant location of these lesions in the small bowel makes them difficult to diagnose. We report the successful use of balloon enteroscopy in conjunction with conventional methods for clinical diagnosis of jejunal GISTs in a 70-year-old man with NF1 who presented with melaena. The importance of screening NF1 patients for GISTs and the complementary role of balloon enteroscopy with capsule endoscopy in such diagnoses is discussed.

摘要

I型神经纤维瘤病（NF1）是最常见的遗传性疾病之一，与胃肠道间质瘤（GIST）风险增加相关。然而，这些病变在小肠的主要位置使其难以诊断。我们报告了在一名70岁患有NF1且出现黑便的男性患者中，成功使用气囊小肠镜结合传统方法对空肠GIST进行临床诊断的情况。讨论了对NF1患者进行GIST筛查的重要性以及气囊小肠镜与胶囊内镜在此类诊断中的互补作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/897f5f8f7c4d/crg0005-0308-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/a91042fd2602/crg0005-0308-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/32ad2c966f98/crg0005-0308-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/897f5f8f7c4d/crg0005-0308-f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/a91042fd2602/crg0005-0308-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/32ad2c966f98/crg0005-0308-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6073/3124322/897f5f8f7c4d/crg0005-0308-f03.jpg

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本文引用的文献

1
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J Am Acad Dermatol. 2009 Jul;61(1):1-14; quiz 15-6. doi: 10.1016/j.jaad.2008.12.051.
2
Small bowel enteroscopy: territory conquered, future horizons.小肠肠镜检查：已攻克的领域，未来的前景
Curr Opin Gastroenterol. 2009 Mar;25(2):110-5. doi: 10.1097/MOG.0b013e3283260916.
3
Gastrointestinal stromal tumour.胃肠道间质瘤
Lancet. 2007 May 19;369(9574):1731-41. doi: 10.1016/S0140-6736(07)60780-6.
4
Two von Recklinghausen's disease cases with pheochromocytomas and gastrointestinal stromal tumors (GIST) in combination.两例伴有嗜铬细胞瘤和胃肠道间质瘤（GIST）的冯雷克林霍增氏病病例。
Int J Urol. 2007 Jan;14(1):73-4. doi: 10.1111/j.1442-2042.2006.01601.x.
5
Gastrointestinal stromal tumors in patients with neurofibromatosis 1: a clinicopathologic and molecular genetic study of 45 cases.1型神经纤维瘤病患者的胃肠道间质瘤：45例临床病理及分子遗传学研究
Am J Surg Pathol. 2006 Jan;30(1):90-6. doi: 10.1097/01.pas.0000176433.81079.bd.
6
Comparison of capsule endoscopy and enteroscopy with the double-balloon method in patients with obscure bleeding and polyposis.胶囊内镜与双气囊小肠镜检查法在不明原因出血和息肉病患者中的比较。
Endoscopy. 2005 Sep;37(9):827-32. doi: 10.1055/s-2005-870207.
7
NF1-associated gastrointestinal stromal tumors have unique clinical, phenotypic, and genotypic characteristics.与1型神经纤维瘤病相关的胃肠道间质瘤具有独特的临床、表型和基因型特征。
Am J Surg Pathol. 2005 Sep;29(9):1170-6. doi: 10.1097/01.pas.0000159775.77912.15.
8
Video capsule endoscopy for investigation of obscure gastrointestinal bleeding: feasibility, results, and interobserver agreement.用于不明原因胃肠道出血检查的视频胶囊内镜：可行性、结果及观察者间一致性
Endoscopy. 2005 Jul;37(7):617-21. doi: 10.1055/s-2005-861419.
9
Diagnosis of gastrointestinal stromal tumors: a consensus approach.胃肠道间质瘤的诊断：一种共识方法。
Int J Surg Pathol. 2002 Apr;10(2):81-9. doi: 10.1177/106689690201000201.
10
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Virchows Arch. 2001 Jan;438(1):1-12. doi: 10.1007/s004280000338.