Khozhaĭ L I, Puchkov V F
Arkh Anat Gistol Embriol. 1990 May;98(5):83-6.
Sensitivity of mouse embryos (8-11 days old) to sodium diethyldithiocarbamate (SDDC), inhibitor of dopamine -beta-hydroxylase, has been investigated. SDDC produces certain anomalies in development of the CNS, facial skull, mandible , extremities and others. It is possible that the base of the mechanism, stimulating development of these anomalies, together with the other causes, can be some disturbances in catecholamine metabolism. This, in its turn, can result in disorders of cell interactions via neurotransmitters during active morphogenetic processes.
已对8至11日龄小鼠胚胎对多巴胺-β-羟化酶抑制剂二乙基二硫代氨基甲酸钠（SDDC）的敏感性进行了研究。SDDC会在中枢神经系统、面颅骨、下颌骨、四肢等的发育过程中产生某些异常。引发这些异常发育的机制基础，连同其他原因，可能是儿茶酚胺代谢的某些紊乱。反过来，这可能会在活跃的形态发生过程中导致通过神经递质的细胞相互作用紊乱。
