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[死亡儿童的急性呼吸道感染及弥漫性血管内凝血综合征在这些疾病中的作用]

[Acute respiratory infections in children who have died and the role of the DIC syndrome in these diseases].

作者信息

Tsinzerling A V, Anisimova Iu N, Ioakimova N V

出版信息

Arkh Patol. 1990;52(6):7-12.

PMID:2171469
Abstract

The results of several years study of the acute respiratory infections (ARI) (pneumonias) are summarized. Their high frequency in dying children is found (72% of autopsy cases in all Leningrad pediatric hospitals). Their etiology is usually complex: viral ARI were in 62.9%, bacterial--56.1%, mycoplasma--8.9%. Structural changes are described in some poorly known ARI (herpetic, cytomegalic, pneumocystic). The distribution of various ARI between hospitals and the etiology of children pneumonia in cases of the death at home (381 cases) or in hospitals (447 cases) are analysed when the autopsy was performed in the same pathology department with detail laboratory investigation. Pneumonias in these groups differed in the etiology and manifestations, first because of bacterial infections. In 114 children the incidence and manifestations of DIC syndrome were studied and this syndrome was shown to have a considerable importance in thanatogenesis particularly during first days of the disease and when the generalization of infections occurs.

摘要

总结了对急性呼吸道感染(ARI)(肺炎)数年的研究结果。发现其在死亡儿童中发生率很高(在列宁格勒所有儿科医院的尸检病例中占72%)。其病因通常很复杂:病毒性ARI占62.9%,细菌性占56.1%,支原体性占8.9%。描述了一些鲜为人知的ARI(疱疹性、巨细胞性、肺孢子虫性)的结构变化。当在同一病理科进行尸检并进行详细实验室检查时,分析了各医院之间不同ARI的分布情况以及在家中死亡(381例)或在医院死亡(447例)的儿童肺炎的病因。这些组中的肺炎在病因和表现上有所不同,首先是由于细菌感染。对114名儿童的弥散性血管内凝血(DIC)综合征的发生率和表现进行了研究,结果表明该综合征在死因形成中具有相当重要的意义,尤其是在疾病的最初几天以及感染发生播散时。

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