Department of Obstetrics and Gynecology, McGill University Health Center, Montreal, QC, Canada.
J Perinat Med. 2011 Sep;39(5):495-8. doi: 10.1515/jpm.2011.059. Epub 2011 Jun 30.
To identify risk factors for postpartum hemorrhage (PPH) in low risk patients.
All deliveries between 2001 and 2007 were retrieved. Women with well-established preexisting risk factors for PPH were excluded. Among the remaining women (n=15,198) considered at low risk, various factors were assessed to evaluate their role in PPH.
Rates of PPH increased from 1.03 in 2001 to 2.45% in 2007. Gestational age at delivery, induction of labor with oxytocin, cesarean section and regional analgesia were not associated with PPH. Logistic regression analysis demonstrated that the following factors were significantly associated with PPH: increased birth weight (P<0.001), female gender (P=0.006), duration of membrane rupture (P=0.002), duration of second stage (P<0.001), chorioamnionitis (P=0.02), and use of prostaglandins (P=0.041).
Early recognition of the specific factors presented as associated with PPH should prompt early intervention to reduce the PPH and maternal morbidity.
确定低危产妇产后出血（PPH）的风险因素。
检索 2001 年至 2007 年间所有分娩病例。排除具有明确的 PPH 高危因素的产妇。在其余被认为是低危的 15198 名女性中，评估了各种因素，以评估它们在 PPH 中的作用。
PPH 发生率从 2001 年的 1.03%上升至 2007 年的 2.45%。分娩时的胎龄、催产素引产、剖宫产和区域镇痛与 PPH 无关。Logistic 回归分析显示，以下因素与 PPH 显著相关：出生体重增加（P<0.001）、女性（P=0.006）、胎膜破裂时间（P=0.002）、第二产程时间（P<0.001）、绒毛膜羊膜炎（P=0.02）和前列腺素的使用（P=0.041）。
早期识别与 PPH 相关的特定因素，应及时采取干预措施，以降低 PPH 和产妇发病率。
