Department of Organic Chemistry, University of Madras, Chennai, India.
Carbohydr Res. 2011 Sep 27;346(13):1776-85. doi: 10.1016/j.carres.2011.06.001. Epub 2011 Jun 13.
A series of fluorescein-based N-glycosylamines was synthesized from the corresponding fluorescein amine and a partially protected d-glucose. The physiochemical investigation of these compounds by spectral and morphological studies reveals their gelation potential. The exclusive localization of fluorescence in the cytoplasm through cell imaging studies reveals the anti-cancer potentials of N-glycosylamines.
从相应的荧光胺和部分保护的 D-葡萄糖合成了一系列基于荧光素的 N-糖基胺。通过光谱和形态研究对这些化合物的物理化学研究揭示了它们的凝胶化潜力。通过细胞成像研究发现荧光素在细胞质中的特异性定位，揭示了 N-糖基胺的抗癌潜力。
