Durand-Malgouyres C, Bazex J, Marguery M C
Service de Dermatologie Hôpital La Grave, Toulouse.
Allerg Immunol (Paris). 1990 Sep;22(7):271-3.
For the same symptoms, (following pruritus without a cutaneous lesion, after contact with water), we must recognise three different etiological circumstances. The physio-pathologies differ in the three cases, as well as their therapy. in aquagenic pruritus of the aged, due to senile sclerosis, the skin must be rehydrated with efficacy but at the same time non-aggressively. in aquagenic pruritus of polyglobulins, therapeutic efficacy of aspirin raises suspicion of involvement of prostaglandins. Idiopathic aquagenic pruritus in young subjects is due to combination of the actions of several chemical mediators. The choice of therapy is difficult and depends on the effect of the addition of bicarbonate of soda to the bath water.
对于相同的症状（如无皮肤损害的瘙痒，接触水后），我们必须认识到三种不同的病因情况。这三种情况的生理病理学不同，治疗方法也不同。在老年患者的水源性瘙痒中，由于老年性硬化，皮肤必须有效补水，但同时不能过于刺激。在多球蛋白血症的水源性瘙痒中，阿司匹林的治疗效果引发了对前列腺素参与的怀疑。年轻患者的特发性水源性瘙痒是由几种化学介质的联合作用引起的。治疗方法的选择很困难，这取决于在 bath water 中添加小苏打水的效果。 （注：原文中“bath water”直接保留英文，可能有误，推测应为“bathwater”，即“洗澡水” ）
